Low Anion Gap

Posted by sallylynn @sallylynn, Sep 13, 2023

I just had blood work done on 09/11/2023. Basic Metabolic Panel. The one that concerned me was Anion Gap. The normal range is 7-13. Mine was 6. On August 24, 2023, 18 days earlier, it was 11. My Anion Gap dropped 5 numbers. I contacted my Doctor with my rightful concerns, hence it is considered "Very rare" to have a below normal Anion Gap. My Doctor was quite "Nonchalant" and told me this it is "Normal" and numbers can slightly fluctuate and "Not to worry", well, I am and that is no small fluctuation! **Mayo claims IF your Anion Gap is "Below normal", your doctor should order a re-test to rule out "Lab error". She did NOT even consider this! I asked her to do a re-test to rule out any disease or cancer, if she doesn't, I may call the Supervisor of the Clinic. I have to literally beg. Your thoughts or opinions would be great. If a hematologist see's this post, I would like your opinion.

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@sallylynn

Thank you so much for responding~ I really appreciate it. I should mention my Creatinine was .095 (Normal) on Aug.24, and on Sept. 11 it was 1.05, a bit over average. My eGFR was 68 on Aug.24, and dropped to 60 on Sept.11.- On August 24 my Albumin was 3.6(Normal) my Platelets were 227(Normal) My WBC was 3.6(Below Average). My Red Cell Count was 4.1M/ul(Normal). These are my Anion Gap numbers of recent, starting from most recent: 6,11,11,11,8,7,9,12,11,11.
So, too see 6 was shocking. Nothing has changed in my intake of Protein. The only thing I am doing different now is taking vitamin B12 500mcg per day. I should mention on July 26, out of no where, I developed a neuropathy. Two days later, my ankle bones were aching. I was diagnosed with neuropathy. They gave me Gabapentin. I only took it for 3 days. I started taking B12. My B12 labs were in normal but very low at 268 where the normal low range is 213. My neuropathy got better for awhile, feeling hopeful, but now again my hands tingle, my arms, and body sometimes and I do feel bone pain on and off in my lower legs and ankles. It wakes me up at night. I guess that is why I am worried now with the low Anion Gap. I just find it odd with all those Anion Gaps in the normal range, why it dropped so suddenly. ~ Any advise would be great. Thank you.

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My Anion Gap has been low for the last 6 of 7 CMP tests.
Actually 5 is the highest it’s been…lol 2 to 3 is about the average I’ve see.
And AST, ALT and LIPASE are all real low and aoit of range.

And all I get is the same answer you got,….. all well it could be a false ready, maybe the numbers are off…., try it again… etc etc etc

Mean time I feel like crap lol

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