Thank you for this information
I'm hoping they are going to come up with treatment that will be the one that helps tomorrow when we see the oncologist
I'll mention this if I think they aren't coming up with what is a good alternative
I appreciate your help so very much
Worst time of my life😢
My husband also can't have surgery because of vessel involvement
I think when we go for his first chemo treatment after being off chemo since November while he was having 28 days of radiation that didn't shrink his tumor as was hoped for🙁we might find that he now has lesions on his liver
He had a scan last week that I can see on his patient gateway chart and it shows liver lesions so I was wondering what the oncologist was going to recommend on Wednesday and it sounds like from your comment that he will get chemo..I just want to make sure that they recommend some kind of treatment. Thought I have read on this site that others that have liver lesions from the pan cancer have had chemo for it and I think I have read that it has shrunk the liver lesions,,hope that true❤️
And yes your post has helped a lot!! thank you...a battle every day!
@bceg1969 , I've copied and pasted this from an older discussion. I hope something in it might be helpful...
... this is kind of recent, long-shot stuff, but are you familiar with HAI (Hepatic Artery Infusion)? It's where surgeons implant a pump with a chemo reservoir that has a catheter directly to one of the arteries that feeds the liver.
This context of this video:
is for mets to liver from colorectal cancer and bile duct cancer but _might_ be applicable to pancreatic cancers with the right surgeon/institution.
The video link above features Dr. Michael Cavner, who did his fellowship at MSKCC, and describes how the work there expanded as those fellows graduated and moved to new centers.
I noticed that a fairly new/young surgeon at Mayo Jacksonville, Dr. Katherine Poruk at lists HAI and Whipple among procedures she performs. She did her fellowship at MSKCC and co-published several papers with Dr. Christopher Wolfgang during her residency at Johns Hopkins, so she or someone with similar background might be a good person to discuss options with. https://www.mayoclinic.org/biographies/poruk-katherine-m-d/bio-20545266
In Dr. Cavner's video, he mentions the importance of a pre-infusion saline test to make sure the chemo is _not_going to the pancreas (context again being to treat a colorectal met to the liver), but for someone with a tumor also in the pancreas, it might actually be desired and doable.
I had only read of direct arterial infusion for pancreatic cancers in rats, but they were able to obtain chemo concentrations in the pancreas with 1/300th the dose of what they needed for conventional systemic chemo through a port while minimizing systemic side effects.
My husband also can't have surgery because of vessel involvement
I think when we go for his first chemo treatment after being off chemo since November while he was having 28 days of radiation that didn't shrink his tumor as was hoped for🙁we might find that he now has lesions on his liver
He had a scan last week that I can see on his patient gateway chart and it shows liver lesions so I was wondering what the oncologist was going to recommend on Wednesday and it sounds like from your comment that he will get chemo..I just want to make sure that they recommend some kind of treatment. Thought I have read on this site that others that have liver lesions from the pan cancer have had chemo for it and I think I have read that it has shrunk the liver lesions,,hope that true❤️
And yes your post has helped a lot!! thank you...a battle every day!
I do have lesions on my liver in addition to the main tumor in the body of my pancreas. I probably have lesions elsewhere, for that matter. The lesions don't show up on a CT scan because they're too flat, but the surgeon saw them during my staging laparoscopy. So that makes me a stage 4. I'm not a medical professional, so all I can share is my own experience. In my case, chemo is not only the treatment of choice, it's the only treatment. The lesions and blood vessel involvement around the main tumor exclude me from any sort of surgery (such as the Whipple) or radiation. I did ask about HIPEC, which is a heated abdominal chemo wash, but my MD told me it would make me really sick and he didn't recommend it. I'm having chemo round 20 tomorrow. I'm on modified Folfiri (no oxaliplatin; my MD discontinued it after round 8), and my dosage level is lower than typical because of the side effects I had during round 1. Does that info help at all? Post your questions. There are a lot of really knowledgeable, helpful people on this board!
Connect
Connect
Like
Helpful
Hug
Thank you for this information
I'm hoping they are going to come up with treatment that will be the one that helps tomorrow when we see the oncologist
I'll mention this if I think they aren't coming up with what is a good alternative
I appreciate your help so very much
Worst time of my life😢
-
Like -
Helpful -
Hug
1 Reaction@bceg1969 , I've copied and pasted this from an older discussion. I hope something in it might be helpful...
... this is kind of recent, long-shot stuff, but are you familiar with HAI (Hepatic Artery Infusion)? It's where surgeons implant a pump with a chemo reservoir that has a catheter directly to one of the arteries that feeds the liver.
This context of this video:
is for mets to liver from colorectal cancer and bile duct cancer but _might_ be applicable to pancreatic cancers with the right surgeon/institution.
The video link above features Dr. Michael Cavner, who did his fellowship at MSKCC, and describes how the work there expanded as those fellows graduated and moved to new centers.
I noticed that a fairly new/young surgeon at Mayo Jacksonville, Dr. Katherine Poruk at lists HAI and Whipple among procedures she performs. She did her fellowship at MSKCC and co-published several papers with Dr. Christopher Wolfgang during her residency at Johns Hopkins, so she or someone with similar background might be a good person to discuss options with.
https://www.mayoclinic.org/biographies/poruk-katherine-m-d/bio-20545266
In Dr. Cavner's video, he mentions the importance of a pre-infusion saline test to make sure the chemo is _not_going to the pancreas (context again being to treat a colorectal met to the liver), but for someone with a tumor also in the pancreas, it might actually be desired and doable.
I had only read of direct arterial infusion for pancreatic cancers in rats, but they were able to obtain chemo concentrations in the pancreas with 1/300th the dose of what they needed for conventional systemic chemo through a port while minimizing systemic side effects.
My husband also can't have surgery because of vessel involvement
I think when we go for his first chemo treatment after being off chemo since November while he was having 28 days of radiation that didn't shrink his tumor as was hoped for🙁we might find that he now has lesions on his liver
He had a scan last week that I can see on his patient gateway chart and it shows liver lesions so I was wondering what the oncologist was going to recommend on Wednesday and it sounds like from your comment that he will get chemo..I just want to make sure that they recommend some kind of treatment. Thought I have read on this site that others that have liver lesions from the pan cancer have had chemo for it and I think I have read that it has shrunk the liver lesions,,hope that true❤️
And yes your post has helped a lot!! thank you...a battle every day!
-
Like -
Helpful -
Hug
1 ReactionI do have lesions on my liver in addition to the main tumor in the body of my pancreas. I probably have lesions elsewhere, for that matter. The lesions don't show up on a CT scan because they're too flat, but the surgeon saw them during my staging laparoscopy. So that makes me a stage 4. I'm not a medical professional, so all I can share is my own experience. In my case, chemo is not only the treatment of choice, it's the only treatment. The lesions and blood vessel involvement around the main tumor exclude me from any sort of surgery (such as the Whipple) or radiation. I did ask about HIPEC, which is a heated abdominal chemo wash, but my MD told me it would make me really sick and he didn't recommend it. I'm having chemo round 20 tomorrow. I'm on modified Folfiri (no oxaliplatin; my MD discontinued it after round 8), and my dosage level is lower than typical because of the side effects I had during round 1. Does that info help at all? Post your questions. There are a lot of really knowledgeable, helpful people on this board!
-
Like -
Helpful -
Hug
6 Reactions