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Anyone have experience with liver lesions from pancreatic cancer?
Pancreatic Cancer | Last Active: Apr 12 12:26pm | Replies (63)Comment receiving replies
My husband also can't have surgery because of vessel involvement
I think when we go for his first chemo treatment after being off chemo since November while he was having 28 days of radiation that didn't shrink his tumor as was hoped for🙁we might find that he now has lesions on his liver
He had a scan last week that I can see on his patient gateway chart and it shows liver lesions so I was wondering what the oncologist was going to recommend on Wednesday and it sounds like from your comment that he will get chemo..I just want to make sure that they recommend some kind of treatment. Thought I have read on this site that others that have liver lesions from the pan cancer have had chemo for it and I think I have read that it has shrunk the liver lesions,,hope that true❤️
And yes your post has helped a lot!! thank you...a battle every day!
Replies to "My husband also can't have surgery because of vessel involvement I think when we go for..."
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@bceg1969 , I've copied and pasted this from an older discussion. I hope something in it might be helpful...
... this is kind of recent, long-shot stuff, but are you familiar with HAI (Hepatic Artery Infusion)? It's where surgeons implant a pump with a chemo reservoir that has a catheter directly to one of the arteries that feeds the liver.
This context of this video:
https://youtu.be/srP9mZVGuec?si=BeC5aJk-H4a5ico5
is for mets to liver from colorectal cancer and bile duct cancer but _might_ be applicable to pancreatic cancers with the right surgeon/institution.
The video link above features Dr. Michael Cavner, who did his fellowship at MSKCC, and describes how the work there expanded as those fellows graduated and moved to new centers.
I noticed that a fairly new/young surgeon at Mayo Jacksonville, Dr. Katherine Poruk at lists HAI and Whipple among procedures she performs. She did her fellowship at MSKCC and co-published several papers with Dr. Christopher Wolfgang during her residency at Johns Hopkins, so she or someone with similar background might be a good person to discuss options with.
https://www.mayoclinic.org/biographies/poruk-katherine-m-d/bio-20545266
In Dr. Cavner's video, he mentions the importance of a pre-infusion saline test to make sure the chemo is _not_going to the pancreas (context again being to treat a colorectal met to the liver), but for someone with a tumor also in the pancreas, it might actually be desired and doable.
I had only read of direct arterial infusion for pancreatic cancers in rats, but they were able to obtain chemo concentrations in the pancreas with 1/300th the dose of what they needed for conventional systemic chemo through a port while minimizing systemic side effects.