Liver Directed Therapy - Y-90 or Chemoembolization

Posted by alanbeavfan @alanbeavfan, Aug 12 7:15pm

I am quite a rare case here with S4 PACC with a tail mass with RET positive genetic indication and mets liver. I have had a very good response to Retevmo/Selpercatinib. 50% reduction in diameter of all tumors (~80% reduction by volume). Happy with this result though the shrinking has slowed and/or stopped. The order of priority is to manage the lesions in the liver first and then go after the tumor on the tail.

I am reaching out to see if anyone has had either Y-90 or Chemoembolization procedures? I would love to hear your experience as this is thought to be my next step. (Even with the reductions my liver tumors are still too large and numerous for Histotripsy. )

Thank you!

Interested in more discussions like this? Go to the Pancreatic Cancer Support Group.

@alanbeavfan Here is a link to previous conversations on Y90. Take a look at them. Let us know what questions you have?
- Radioembolization vs Y90: Are they the same? Results? https://connect.mayoclinic.org/discussion/radioembolization-vs-y90/
- Has anyone had Y90 treatment for NETS? https://connect.mayoclinic.org/discussion/has-anyone-had-y90-treatment-for-nets/
- I'm having Y-90 procedure: What can I expect step-by-step? https://connect.mayoclinic.org/discussion/im-having-the-y-90-procedure-friday-3/

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Profile picture for Turkey, Volunteer Mentor @tomrennie

@alanbeavfan Here is a link to previous conversations on Y90. Take a look at them. Let us know what questions you have?
- Radioembolization vs Y90: Are they the same? Results? https://connect.mayoclinic.org/discussion/radioembolization-vs-y90/
- Has anyone had Y90 treatment for NETS? https://connect.mayoclinic.org/discussion/has-anyone-had-y90-treatment-for-nets/
- I'm having Y-90 procedure: What can I expect step-by-step? https://connect.mayoclinic.org/discussion/im-having-the-y-90-procedure-friday-3/

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@tomrennie Thank you very much! I need to get better at searching the existing posts!

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After about 9 months of fulfurinox we did Y90. It worked great and got me to pancreatic surgery!

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Profile picture for alanbeavfan @alanbeavfan

@tomrennie Thank you very much! I need to get better at searching the existing posts!

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@alanbeavfan No worries. If you scroll to the top, click on the magnifying glass. It will give you the opportunity to input search criteria. Once done, click on the magnifying glass again. You should get your search results. Let me know how that works for you.

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Profile picture for alanbeavfan @alanbeavfan

@tomrennie Thank you very much! I need to get better at searching the existing posts!

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@alanbeavfan How is your research on Y90 going?

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