1. < Breast Cancer

Letrozole and Neuropathy

Posted by vtgal @vtgal, Apr 24, 2023

Has anyone experienced neuropathy after starting Letrazole? I was diagnosed with neuropathy soon after starting on Letrazole. It has moved from my feet to my hands now. It is disabling and painful. Thanks

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mcaj | @mcaj | Jan 1 6:18pm
In reply to @dlmdinia "I was on Letrozole for 9 months before chemo. The only side effect I had was..." + (show)
@dlmdinia

I was on Letrozole for 9 months before chemo. The only side effect I had was hot flashes. My neuropathy is chemo induced and improved somewhat after chemo finished. I'm off Letrozole in two months and looking forward to some (hopefully) real improvements in the next year. I'm also transitioning off Prolia which I think may be sharing the blame for a lot of my joint issues. I'm blaming Letrozole (or any AI, I've been on all 3) for insomnia, brain fog, elevated lipid levels, moodiness, inability to lose weight, and probably more. But after the initial improvement of my neuropathy after finishing chemo (about a year), my neuropathy has worsened only slightly in the last year. (I finished chemo 4 years ago).

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Hope you've kept records (journal) of your experiences. Hope it helps others down the road that truly have issues with the gold standard of treatment at the time it happens. Been there, done that and it's been since 1997.......
3 times thus far.

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