Leaky gut syndrome?

Posted by davejscott @davejscott, Oct 13, 2018

"Leaky gut" seems to be fairly tropical at the moment. I wonder if the attention is warranted.

Hi @davejscott and welcome to Connect!

You're right. Leaky gut syndrome is hotly debated at this time.

Here are various opinions on leaky gut:

– Is Leaky Gut Syndrome a Real Condition? An Unbiased Look (Healthline) https://www.healthline.com/nutrition/is-leaky-gut-real

– Debunking the Myth of ‘Leaky Gut Syndrome’ (GI Society) https://www.badgut.org/information-centre/a-z-digestive-topics/leaky-gut-syndrome/

– Leaky gut: What is it, and what does it mean for you? (Harvard Medical School) https://www.health.harvard.edu/blog/leaky-gut-what-is-it-and-what-does-it-mean-for-you-2017092212451

Gastroenterology & GI Surgery Page on Connect has some great videos about leaky gut, by Mayo Clinic experts: https://connect.mayoclinic.org/page/gastroenterology-and-gi-surgery/ Like this one by Dr. Murray.

– Is Larazotide Acetate the Answer to Leaky Gut? https://connect.mayoclinic.org/page/gastroenterology-and-gi-surgery/newsfeed/is-larazotide-acetate-the-answer-to-leaky-gut-1/

@davejscott, is this a condition that you or someone you know is experiencing?

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Thank you so much for this info. This has been very helpful! I see this OP is from 2018. Is there newer research or information on this topic? Has the debate been settled whether leaky gut is legitimate for patients who do not have celiac disease?

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davejscott, intestinal permeability may be a result of a thiamine deficiency. So asking about "Leaky Gut" may have brought you to learning more about this remarkable vitamin that requires magnesium to become bioactive..
https://www.eonutrition.co.uk/post/thiamine-deficiency-a-major-cause-of-sibo
https://nootropicsexpert.com/vitamin-b1-thiamine/

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@eslavik1

Thank you so much for this info. This has been very helpful! I see this OP is from 2018. Is there newer research or information on this topic? Has the debate been settled whether leaky gut is legitimate for patients who do not have celiac disease?

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Welcome to Mayo Clinic Connect, @eslavik1. Mayo Clinic has done a recent study with significant findings I thought you would like to read this article.
Understanding the role of proteolytic activity in mediating irritable bowel syndrome symptoms and disruption of intestinal barrier function https://www.mayoclinic.org/medical-professionals/digestive-diseases/news/understanding-the-role-of-proteolytic-activity-in-mediating-irritable-bowel-syndrome-symptoms-and-disruption-of-intestinal-barrier-function/mac-20485226

Have you been given an official diagnosis for anything yet, @eslavik1?

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No I haven't. In the stage of going through numerous tests to rule out things at the VA. Doing my own preliminary research.

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@eslavik1 Good for you! I think it is so important to be on top of your medical health as much as possible. Physicians are people just like everyone else and though I have the utmost respect for their profession, they can't always be the experts in everything. Being your own advocate is always the best backup when it comes to your health and body. I like to say, "I am the one that knows me best!"

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@amandaburnett

@eslavik1 Good for you! I think it is so important to be on top of your medical health as much as possible. Physicians are people just like everyone else and though I have the utmost respect for their profession, they can't always be the experts in everything. Being your own advocate is always the best backup when it comes to your health and body. I like to say, "I am the one that knows me best!"

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Is there any research on the role of leaky gut and rheumatoid arthritis? Or any research on how to actually heal a leaky gut? I know there’s a lot written about the autoimmune protocol diet. Is there a definitive AIP, s there seem to be several variations out there?

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