Kevzara experiences?

Posted by margedoc @margedoc, Sep 25, 2025

I have been on a combination of prednisone and methotrexate for PMR and because of relapses when I get to 5 mg. of prednisone plus methotrexate side effects (fatigue, hair loss), I am being started on Kevzara with the goal of tapering off the other drugs. I'd be interested in others' experiences with Kevzara.
Marge

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

stonewheel | @stonewheel | Jan 14 7:09am

In reply to @tweetypie13 "Look for my previous posts. 79 yo woman, PMR diagnosed April 2024. I was stuck at..." + (show)

@tweetypie13 you are such an inspiration to me, Thank you for your shares.

aussiedogmom | @aussiedogmom | Jan 14 8:26am

My friend with Psoriatic Arthritis and my PT told me about it before I got to the rheumatologist. Dr Rheum supports it.

richardab | @richardab | Feb 2 2:05pm

Another update. I’m now taking 1/2 mg Prednisone every other day and will get off it completely starting March 1. No PMR backlash. At the next rheumy visit, we’ll discuss if the Kevzara can be spaced out further than 2 weeks apart.

tweetypie13 | @tweetypie13 | Feb 2 5:18pm

In reply to @richardab "Another update. I’m now taking 1/2 mg Prednisone every other day and will get off it..." + (show)

@richardab
I was 3 months off prednisone when I went to every 3 wks Kevzara.
Good luck

lsa22 | @lsa22 | Feb 4 11:05am

I was diagnosed in June 2025, as a complication from a medication. My highest prednisone does was 30 mg. I started Kevzara injections in August and was off prednisone by October. In January I went to ER with acute diverticulitis, and was advised to stop Kevzara. It has been 6 weeks since my last injection. I do not have pmr symptoms, but my muscles seem to fatigue and are just not as strong. I am trying to regain the strength but at times want to give up. My rheumatologist indicates that remission is trickly and fleeting...
"There is no time period for remission. Overall the data suggests that you have your best chance at long term remission if you had 1 year of treatment and then taper off. Some people need less time, but in general the faster it comes under control the more likely it is to stay in remission. Right now you are a high risk for recurrence over the next 3-6 months, after that the risk goes down, but only time will tell. Even with good remission, overall there is a 20% recurrence rate. Unfortunately we just won't know until time has passed and there is no test to tell me."