Jak2 and Vitamin D3

I have PCV and Jak 2 positive. At the moment I am seeing two oncologist one in Florida when I am there at a cancer Institute, and one up in Wisconsin when I am there. Neither one has mentioned taking any supplements at this time. I take 500 mg of hydroxy, three times a week, and a baby aspirin every morning. I’m lucky I feel like 1 million bucks. Until they bring it up I’m not going to upset the Apple cart.

Last year my primary had me tested for B12, so now that's on my daily intake

Ditto! I’m recently diagnosed with the same one year ago and am on the same regimen. I’m hoping to keep the dosage low. In the beginning it was 7x a week and I felt the side effects. So much better with the lower dose. Fingers crossed for us both!

Same situation with me….. Missouri in the summer, Florida in the winter. It has been suggested several times about hydroxyurea. My hair is already thin and I don’t want it to get any thinner. If it would make me feel stronger, I
m i g h t consider it. I am exhausted and used to be willing to go shopping anytime. That enjoyment is gone, due to my weakness, I must use a walker if I go into a store, or a mobility cart, if available. I rarely have to have phlebotomies anymore with my hematocrit low to mid 40s. Neither hematologist offers. Any suggestions for my lack of strength except “exercise”
How is that possible when I am so weak I can barely walk 50 feet without exhaustion? I do ride an adult trike daily in Florida. I take multiple naps a day sometimes, but feel they are necessary. I have asked about a support group, but none are in either area. Fatigue is constant, Anyone have suggestions?

I have essential thrombocythemia, with JAK2 gene. Diagnosed in 2022 after a emergency gall bladder operation. I've been on Hydroxyurea 500 mg 2x a day. I am asking if anyone has been warned against the RSV vaccination. I was, by a medical professional. It was also suggested that there was is a possible link to the thrombocythemia and the Covid vaccinations?? Has anyone else heard this? My insurances do not cover the RSV vaccination and the cost is $350+ so I'm not in any hurry to get it. However, just had a cousin die from this infection. He did have a compromised condition of being overweight. Not looking for conspiracy theories just some information/insights from those of us in the same boat. Thank you.

I have taken Bcomplex since 1970
Recently my dr told me to lower the dose to every other day. It was too high
I have Jak2 for high platelets about 2 years on Hydria 500 3x week.
Platelets good now

I have not heard about a link between JAK2 and the COVID-19 vaccinations. When my doctor told me I had the JAK2 genetic mutation I thought I was going to get superpowers like Spiderman. No sign of superpowers yet after 6 years of being diagnosed. I've been on Hydroxyurea 500 mg 2x a day then lowered to 1x a day. Platelets are under control now. I had Polycythemia Vera (PV) long before the COVID was unleashed on the world so I am not sure of a link there. I will be going to my doctor soon and will ask about the RSV vaccination. I wish you the best.