Ivermectin for Prostate Cancer? (Being studied)

Posted by tvz @tvz, Apr 7, 2024

I am 54 and have Gleason 3+4 in 8% of one lobe. My PSA rose from 8.1 to 9.6 in the past 6 months. I’ve heard Ivermectin has potential to slow growth of cancer cells. Has anyone tried IVM or any other medication that has been shown to slow growth?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Bob here with a question.

How much ivermectin do you take a day and for how long? I've been taking it for 3 months but don't really know the proper dose.

REPLY
@northoftheborder

It's great that there's research ongoing on meds related to Ivermectin, and that some oncologists are advocating for even more. But it's important to remember that reliable scientific evidence doesn't exist yet, and if it does eventually emerge, the effective dosage, formulations, and indications/contra-indications could be dramatically different from what people are (dangerously) trying to self-dose with right now.

Jump to this post

I would gently push back on a couple of those points.

Safe dosing has been established for a long time. It's included in the FDA prescribing information document. There is no reason, short of interactions that would intensify ivermectin's area under the curve, for the safe dosing levels to be different from what is specified for it's primary purpose.

Drug-drug interactions are also detailed in the prescribing info document. Most are specified in terms of the enzymes that metabolize ivermectin or the other drug that's being checked against it. This type of data is also specified in the prescribing information for common PCa meds. Not everyone can read that and comprehend what they need to, so it is simple enough to ask a pharmacist or your GP. As an example, I just checked the meds I take, which is quite a few, and some other common PCa meds, and found only one moderate interaction: Enzalutamide decreases the AUC of ivermectin. So, changing it in the safe direction.

Indications? I'm going to die in several months because all my PCa therapies failed, and would like to try Ivermectin.

Contraindications? Again, see the FDA prescribing info.

I'm not taking it anytime soon as I don't need to take any other meds. I just don't think it is reasonable to throw up a bunch of red flags to patients who are otherwise out of options. I would be cautious about taking it in early stages of the disease without some level of guidance from a medical professional.

REPLY
@russ777

I would gently push back on a couple of those points.

Safe dosing has been established for a long time. It's included in the FDA prescribing information document. There is no reason, short of interactions that would intensify ivermectin's area under the curve, for the safe dosing levels to be different from what is specified for it's primary purpose.

Drug-drug interactions are also detailed in the prescribing info document. Most are specified in terms of the enzymes that metabolize ivermectin or the other drug that's being checked against it. This type of data is also specified in the prescribing information for common PCa meds. Not everyone can read that and comprehend what they need to, so it is simple enough to ask a pharmacist or your GP. As an example, I just checked the meds I take, which is quite a few, and some other common PCa meds, and found only one moderate interaction: Enzalutamide decreases the AUC of ivermectin. So, changing it in the safe direction.

Indications? I'm going to die in several months because all my PCa therapies failed, and would like to try Ivermectin.

Contraindications? Again, see the FDA prescribing info.

I'm not taking it anytime soon as I don't need to take any other meds. I just don't think it is reasonable to throw up a bunch of red flags to patients who are otherwise out of options. I would be cautious about taking it in early stages of the disease without some level of guidance from a medical professional.

Jump to this post

I think we're on the same page here. My concern is also people self-dosing with an unproven treatment when they still have lots of medical options open (and potentially years or decades of quality life ahead), which even applies to many of us with stage 4 these days. But I also recognise that they have the final say.

REPLY
@rwj613

Bob here with a question.

How much ivermectin do you take a day and for how long? I've been taking it for 3 months but don't really know the proper dose.

Jump to this post

good question, we're in the situation regarding IVM. However, I learned that another anti parasitic drug may be more effective, Phenbendazal.
A fellow on here said his PSA numbers went way down after doing the following protocol...
One 222mg pill in the morning and one at night with food for three weeks.
Look into it , I've ordered some from Amazon, it's arriving today...

Good luck

REPLY

I see it spelled with a "Ph" sometimes. Is it the same?

REPLY

I think it is . Most common is FenBen . 222MG seems to be popular dose per caplet . I wonder if yoru Dr could source it for you after you ask him if OK you can take it ? Here in Canada most doctors will give you a place where you can buy medicines not normal at Pharmacy etc .... At our hospitals and some clinics, these things are free of charge like IV drips, pills while you're in the clinic and hospital, and other stuff. Some people stay in the hospital as long as possible now in Canada, because all their meals and drugs, and everything else is taken care of. If you step outside of the hospital/clinic , sometimes you'll have to pay for certain medication's and definitely your meals for sure , HA!!! 🙂 . Our Cancer clinic in Victoria has Super great meals ! Amazing fresh organic meals made 3 times a day , PLUS snacks made too ! Cant beat the care there . Very nice people too ! At that clinic, they get the medicine for you and arrange everything including your doctor visits and stuff. I was there during my 22 sessions of radiation. They said I had to share a room with somebody but I had a room all to myself. Amazing great treatment. .But I don't know how your jurisdiction works. I know the golden rule is always asked the doctor first.

REPLY
@dannos

good question, we're in the situation regarding IVM. However, I learned that another anti parasitic drug may be more effective, Phenbendazal.
A fellow on here said his PSA numbers went way down after doing the following protocol...
One 222mg pill in the morning and one at night with food for three weeks.
Look into it , I've ordered some from Amazon, it's arriving today...

Good luck

Jump to this post

Thanks much Danny's,
My PC was caught late , metastasis over my bones 5-4 Gleason bad reaction to Docetaxel 3second flat, I'm 77 so I was put on nubeqa for a year now I'm off that too , I've started ivermectin and fenben.

REPLY

Thanks, I’m in Langley and have just recently been diagnosed. I’ve ordered Phenben 222. It’s arriving today and I have a phone appointment with my GP on the 30th. I have my first appointment at the X clinic on September 10. I’ll bring it there for them to look at first but I’m pretty much sold on it…

REPLY

What I keep finding for sale is spelled Phenben. Is it the same?

REPLY
@rwj613

Thanks much Danny's,
My PC was caught late , metastasis over my bones 5-4 Gleason bad reaction to Docetaxel 3second flat, I'm 77 so I was put on nubeqa for a year now I'm off that too , I've started ivermectin and fenben.

Jump to this post

What dosages are you taking? I’m 52 btw…

REPLY
Please sign in or register to post a reply.