It's been a year and a half, still undiagnosed. Need some help.
* **Any existing relevant medical issues:** Anxiety, Depression, Vasovagal Syncope, Parenchymal Liver Disease, Micturition Syncope, Mild COPD, IBS.
* **Symptoms:** Hypogastric cramps, memory loss, fatigue, sharp random jolts pain in colon, tachycardia, yellow stool, constipation, diarrhea, sore neck, lower back pain, Terry's nails (hands and feet), cold hands and feet, drop in oral temperature (as low as 93.3), sensitivity to heat and cold temperature, constant dizziness, and cognitive function is declining. Every morning I wake up, my eyes feel like they do after you've been in a chlorinated pool.
* **Current medications:** Vitamin D3 50,000 IU
**Summary:** I'm one of those undiagnosed people floating around after seeing numerous doctors, trying numerous medications and treatments and even multiple diets with no luck.
**Backstory:** I've always been told I just have anxiety and IBS because that's how most of my life has been. Random hypogastric cramping due to not being able to have a bowel movement. Usually, it was constipation, followed by diarrhea. Like a cork in a wine bottle. If I couldn't get the cork out, to get the wine out, I would faint. Keep in mind this was not due to straining to have a bowel movement, this is due to the hypogastric cramping pain. If I'm laying in bed and the pain goes on long enough, I will faint in the bed.
*I'll try to keep the story brief.*
**My Story:** 2 years ago I was at the gym doing the leg press. I felt a sharp pain in the colon area, left the machine and didn't think anything of it. I woke up in the middle of the night to urinate. After urinating (and standing) I fainted (Micturition Syncope).
**Heart:** After that day, my health went downhill. While sitting, my heart rate would go as high as 160 bpm. An electrophysiologist examined my 30-day halter monitor report and said the spikes didn't seem to be like anxiety and he's not exactly sure what is causing the spikes. I mentioned pheochromocytoma, and catecholamines were checked but they were normal. No tumor on my adrenals.
**Kidney:** Last week I had my first kidney stone and this week I go to the Urologist. I will take him my stone for further testing.
**Liver:** I told my doctor I had yellow stools, constipation, and Terry's nails. He said "but your hepatic tests were fine and you're not jaundice? You don't do drugs or drink, so why would you have liver issues?" I pushed for an ultrasound and the report came back as "Heterogenous known uniform echo pattern liver seen and findings suggest liver parenchymal disease, further testing is needed"
**Gastro:** I had a colonoscopy done and a benign polyp was removed in my colon. There were also signs of inflammation in the large intestine. IBS was diagnosed. No parasites found in stools.
**Thyroid:** My hormones including testosterone, progesterone, estriol, and thyroid results were all in the normal range. Including the T3 Free and Reverse T3. However, none of my thyroid results are in the recommended ***optimal ranges*** according to top Endocrinologists, but they are in the reference range in my local area. My hands and feet are always cold and that never used to happen until this past year. I was also told that I'm not anemic. During my drop in temperature, I've tested my blood sugar at home and that has always been in normal range. A1c test was also normal.
**Brain:** My cognitive functions are getting worse due to the brain fog, dizziness, and stress on my overall body. An MRI was done but no abnormalities were seen.
**Mental Health:** I was told I have panic disorder when this all started. I was prescribed 5 anti-depressants over a 6 month period to which none of them helped. The last medication I tried was Zoloft caused a serious pain. It felt like my brain was literally on fire. Excruciating to say the least. A week after stopping that medication, I started having depression, which I never had before.
**Sleep:** I sleep 6-8 hours a night but I never feel rested. Just constant fatigue. Sometimes I wake up due to colon pressure, causing sweating and dizziness, and adrenal surges but it's random. But what is consistent is I wake up and my tongue is as dry as a cactus, which indicates I breathe through my mouth when I sleep.
**Abnormal tests from the last year of testing.**
*Vitamin D and Vitamin B1 were low. (Blood)*
*Vitamin B6 was 3x higher than the high range. (not sure why considering I wasn't taking loads of B6) (Blood)*
*Coproporphyrin i and iii were slightly elevated (Urine)*
**Amino Acids:** *Cystathionine was elevated (Urine)*
**Fatty Acid Profile:** *Decenoic acid (High), Vaccenic Acid and Arachidic Acid (Low)*
**Organic Acid Panel:** *Lactic, GLycolic, 3-Hydroxypropionic, 2-Hydroxyisovaleric, 3-Hdroxyisovaleric, Methylsuccinic, Uracil, Glutaric, 3-Methylglutaconic, Malic, 3-Hydroxyadipic, 5-Oxoproline, Citric, and VMA (All Low)*
**Conclusion:** I've been to numerous doctors as you can tell and there hasn't been any direction. Only Mild COPD (due to years of cigarettes but no longer) and Parenchymal Liver Disease. I don't drink or do drugs so I believe whatever is happening to me and stressing my liver is either (A) all vagus /colon related or (B) I have a metabolic disorder or systemic disease of some kind. It's really the only thing that makes any sense to me but I'm not a doctor.
I've been told I'm a complex case and I agree.. I am. Most of my doctors are starting to see that it's not "all in my head" though but connecting the dots is the hardest part and that's why I'm putting this out there.
Thank you for taking the time to read this, I appreciate it 🙂