Is there anyone that had estrogen positive cancer, without use of AI?

Hi - thank you for your reassuring response. It truly helps in my case. I looked up Tymlos and will ask my oncologist when I see him sept. 22. He will start me on Herceptin and probably a bone building drug. Do not like biophosphonates.
Again thank you and truly wish you all the best.🤗

If they want Reclast, ask about a test dose of 20% (1mg). Hydrate well and ask for a slow infusion. Then three months later you can have another infusion at a dose you choose. At least that is the protocol my doc is using to lock in my gains from Tymlos.

Jusst to clarify: I did Tymlos 6 years after my diagnosis. My bones did get worse on letrozole. I would have done Reclast, which may also have preventive effects with cancer, but my doc did not want to prescribe due to afib.

I have been on Letrozole since Feb 2023 and hanging in (57 yrs, ILC, Lumpectomy, Radiation) and osteopenia has worsened. I see my oncologist in Oct and thinking unless osteoporosis no meds to help bones will be prescribe. I'm fearful of impact on jaw etc but perhaps Tymlos is different.?

Hi- wrote down the Reclast information. The test dose sounds interesting. Possibly to determine side effects?Will definitely mention Reclast to oncologist.Should have been more open minded to drug suggestions and kept in mind that suggestions are made on a individualistic basis.Thank you for sharing and giving me more to think about. Will post after my oncologist appointment.

@semurrey Tymlos does not affect dental health/jaw, as you suggested.

I had Estrogen feeding stage 1 breast cancer in December 2009. I got a lumpectomy, calcification removal and mamocyte therapy. A catheter inserted into the lumpectomy site and radiation delivered in through the 5 limb catheter 1 time daily at variable determining spots by the radiation oncologist. It was for 1 week. I took Arimedex every night for 5 years. I have taken various osteopenia and osteoporosis medicine. Im currently on vit d and calcium for the bone density. I am cancer free x 13 Years. I hope this helps.

My sister had a small stage 1 IDC tumore 13 years ago. Surgery + extensive lymph node removal + radiation. She couldn't tolerate Tamoxifen, so she stopped taking it. She's a pretty vital 80YO now.

That is awesome 👏. I have had lumpectomy, chemo and radiation this past year .Still getting Herceptin every 3 weeks no problems. I am going on my 3 rd estrogen blocker pill I can’t take the pain . I am Her 2 + .
My mammogram this past month showed nothing suspicious 🙏👏. I know I need to take this pill for 5 years but really can’t take the joint pain.
I was happy to to read your sister did well.

Try turmeric,500 mg twice a day. It has helped me.