Is there a connection between b6 toxicity and thyroid issues?

Posted by lbishop @lbishop, May 5, 2023

In the fall, I developed a series of odd symptoms, including vertigo, then tinnitus, brain fog, fatigue, muscle spasms, etc. as well as some of the common symptoms of hypothyroidism, including hair loss, constipation, etc. After seeing multiple doctors, one suggested I get my B levels checked. All were normal except for B6, which are extremely high (>250, with normal upper range of 21). I don't take supplements, really. An occasional multi-vitamin. At the same time, my TSH levels are on the rise. My normal is below 3 and they are now at close to 4.5. I've been taking NP Thyroid for more than 10 years at a very low dose. I can't figure out why my B6 levels would be so high, or how they might relate to other test results.

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Profile picture for proudx @proudx

I have the EXACT problem. B6 toxicity from food alone and have hypothyroidism. Your story sounds exactly like mine. I tried cutting back on b6 foods, done tons of labs, taken tbyroid medication, etc. I’ve posted my journey on a Facebook group.

I believe I have a rare form of hypothyroidism called central hypothyroidism that is driving it.

I also have peripheral neuropathy

Anyway we can connect to compare notes and try and find a solution?

If links are allowed I could send you my documented journey and comments from the Facebook group.

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@proudx Hi, recently going thru the same. My health has had odd stuff my whole life. My recent labs: FB6. 605.2. No that is not a typo. It’s a toxic level of B6. My B12 level is also very high. I noticed a trend in prior labs with consistently low Alk Phos levels. Research indicated that I should check B6. It began. I now know I have Hypophosphotasia. HPP. If you have consistently abnormal low alk phos, have your B6 tested. If very high. Genetic testing confirms dx. It is a metabolic issue. I have been to urgent care, ER, and cardiologist. They all know of no treatment except advice to D/C any vitamins, avoid any B vitamins in foods, energy drinks and anything else.

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