Is anyone taking Nuzyra for M. Abscesses or other?

Posted by kathyjjb @kathyjjb, 2 days ago

Nuzyra is a new antibiotic used to treat M. Abscesses. It should be taken after 4 hours of fasting and prior to 2 more hours of fasting. I decided to take at 10 PM, but now I can't sleep. Insomnia is a side effect. I'm taking Linezolid at 6 AM and 6 PM, and Arikayce at 11 AM. Since I want to space out my drugs, now thinking on changing my time. Anyone else having or had this issue? Did the insomnia subside? I'm thinking set alarm for maybe 3 AM and take then? I'm doing good with Linezolid taking with toast in the morning and dinner at night. Though Linezolid is complicated too, since diet should be low or void of Tyramines to help avoid side effects.

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

I can’t answer the question, but am bumping it up to make it easier for those on it to see. I used the the search on the page and see that it’s been discussed a few times. Trying to tag @marthamac who posted. (There were others, but I’m using phone and lost first post trying to tag).
Good luck to you. It sounds like a lot to deal with.

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@pacathy

I can’t answer the question, but am bumping it up to make it easier for those on it to see. I used the the search on the page and see that it’s been discussed a few times. Trying to tag @marthamac who posted. (There were others, but I’m using phone and lost first post trying to tag).
Good luck to you. It sounds like a lot to deal with.

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Thanks so much! I haven't seen Nuzyra at all in these posts. It got M. Abscesses approved in 2022 and looks really promising. I decided to give the 10PM dose another try and only woke up twice during night-so maybe it will continue to approve. Also, I haven't seen anything about limiting Tyramines while taking Linezolid and it may help people out there to ward off some of the side effects-really appreciate the bump up. Kathy

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Here’s one…
https://connect.mayoclinic.org/discussion/length-of-treatment/?pg=2#comment-1261354
I used the little magnifying glass on main page for MAC and bronchiectasis.

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@kathyjjb

Thanks so much! I haven't seen Nuzyra at all in these posts. It got M. Abscesses approved in 2022 and looks really promising. I decided to give the 10PM dose another try and only woke up twice during night-so maybe it will continue to approve. Also, I haven't seen anything about limiting Tyramines while taking Linezolid and it may help people out there to ward off some of the side effects-really appreciate the bump up. Kathy

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Yes, limit tyramine containing foods while taking Linezolid.
I took Omadacycline for Abcessus. Stopped due to change in insurance.

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@reneemc

Yes, limit tyramine containing foods while taking Linezolid.
I took Omadacycline for Abcessus. Stopped due to change in insurance.

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Hi Renee, Thanks for your response. It's expensive without insurance. Did you get rid of your MAB? I may have you confused with someone else-that did?

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Cleared the Abcessus but still test positive for intercellulare.
I’ve been on a variety of antibiotics the last 2 years

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I took the omadacycline for abscessus for at least a year and a half. I took it at 10 pm, so it would be 4 hours after supper, and plenty of time before breakfast. I didn’t have any trouble with insomnia, but it did give me nausea and vomiting. Once I started taking Zofran 30 minutes before the Omadacycline I rarely had any breakthrough nausea.

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@reneemc

Cleared the Abcessus but still test positive for intercellulare.
I’ve been on a variety of antibiotics the last 2 years

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Glad you cleared MAB. I sure hope the Intacellulare clears. I sure hope we get more meds available to us.

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@marthamac

I took the omadacycline for abscessus for at least a year and a half. I took it at 10 pm, so it would be 4 hours after supper, and plenty of time before breakfast. I didn’t have any trouble with insomnia, but it did give me nausea and vomiting. Once I started taking Zofran 30 minutes before the Omadacycline I rarely had any breakthrough nausea.

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Thanks, Martha, for the info. Good to know about the Zofran. This is so depressing, I just started last week.

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