Immunotherapy - Keytruda for colorectal cancer

Posted by brenz @brenz, Apr 17, 2018

Has anyone with stage 4 colon cancer used keytryda and if so can you share your results. Thank you

Hi @brenz, I'm not sure if anyone in the colorectal cancer group has mentioned using Keytruda (pembrolizumab), but there are a couple of discussions in other groups on Connect that you may want to check out.

– Head & Neck Cancer: Keytruda https://connect.mayoclinic.org/discussion/keytruda/
– Melanoma: Keytruda Treatment https://connect.mayoclinic.org/discussion/kytruda-treatment/

Brenz, did your husband's genomic testing qualify him for keytruda? When will he start?

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@colleenyoung

Hi @brenz, I'm not sure if anyone in the colorectal cancer group has mentioned using Keytruda (pembrolizumab), but there are a couple of discussions in other groups on Connect that you may want to check out.

– Head & Neck Cancer: Keytruda https://connect.mayoclinic.org/discussion/keytruda/
– Melanoma: Keytruda Treatment https://connect.mayoclinic.org/discussion/kytruda-treatment/

Brenz, did your husband's genomic testing qualify him for keytruda? When will he start?

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We had the tests done awhile ago and he did qualify but waiting for more current results. Will know in next week or so.

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anyone taking keytruda. ive had 2 treatments with no real side effects. would like to know how others are doing with it.

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@sc1218

anyone taking keytruda. ive had 2 treatments with no real side effects. would like to know how others are doing with it.

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@sc1218, welcome to Connect. You'll notice that I moved your message to this existing discussion about Keytruda and colon cancer. I did this so you can meet @brenz whose husband is also receiving or considering Keytruda treatments for colorectal cancer. Brenz, did he start Keytruda?

SC1218, you may also be interested in this discussion on Connect:
– Immunotherapy and chemo; Keytruda side effects https://connect.mayoclinic.org/discussion/immunotherapy-and-chemo/

Have you had any treatments prior to starting Keytruda? What type and stage is your cancer?

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My husband has stage 4 colon cancer with mets to liver and lungs. He did not qualify for keytruda so we have not had the opportunity to try it. I was praying he would have qualified. I wish you the best and hope you continue to keep us posted as we are in touch with many colon cancer patients outside of this site and would love to share your experiences with them.

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@brenz

My husband has stage 4 colon cancer with mets to liver and lungs. He did not qualify for keytruda so we have not had the opportunity to try it. I was praying he would have qualified. I wish you the best and hope you continue to keep us posted as we are in touch with many colon cancer patients outside of this site and would love to share your experiences with them.

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Im sorry your husband didnt qualify. Im stage 4 with mets to the peritneum, bladder, and lungs. I also was turned down for the last year based on my cancer being caused by chrons disease. In febuary i met two doctors willing to treat me based on my genetic markers. High tumor mutation burden. It took 2 months to get it all together. Im no longer in constant pain, side effects are nothing compared to chemo but that could change. I have my third treatment this week and first scans next week.
Dont give up if you believe imuno can help your husband. If he has any of the known markers for treatment it wont cure him but it might keep it managable.
Good luck.

Liked by tucsonfunnyfarm

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@sc1218 I was wondering how your husband's scans came out and if he continued on Keytruda?

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Hola soy Miguel Ángel de Aguascalientes México. Yo padezco cáncer colorrectal con metástasis en hueso de cadera y pulmón izquierdo. Llevó 4 aplicaciones de keytruda y mi antigeno no ha bajado incluso ha subido ahorita está en 1800. Estoy deseperado

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@miguelsofisanti

Hola soy Miguel Ángel de Aguascalientes México. Yo padezco cáncer colorrectal con metástasis en hueso de cadera y pulmón izquierdo. Llevó 4 aplicaciones de keytruda y mi antigeno no ha bajado incluso ha subido ahorita está en 1800. Estoy deseperado

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Welcome @miguelsofisanti.
Unfortunately, I don't speak Spanish. But I put your message into Google translate (https://translate.google.ca/) so that I can respond to you. I hope you will be able to translate my message into Spanish.

YOU SAID
Hi, I'm Miguel Ángel from Aguascalientes Mexico. I have colorectal cancer with metastases in the hip bone and left lung. It took 4 applications of keytruda and my antigen has not gone down even has risen right now is in 1800. I am desperate

MY REPLY
You are not alone. @lah's husband has a similar experience, which you can read about here:
– Metastasized colon cancer: At a loss..what is next? https://connect.mayoclinic.org/discussion/at-a-loss-what-is-next/
Is your oncologist suggesting a different treatment options?

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@brenz

My husband has stage 4 colon cancer with mets to liver and lungs. He did not qualify for keytruda so we have not had the opportunity to try it. I was praying he would have qualified. I wish you the best and hope you continue to keep us posted as we are in touch with many colon cancer patients outside of this site and would love to share your experiences with them.

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my hunnybunny has ben diagnosed with colon,anus,pubic area and mestestasized to his liver and nodules ion his lungs. how do I stop crying.. how do I get him moving and not giving up?

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@bond007

my hunnybunny has ben diagnosed with colon,anus,pubic area and mestestasized to his liver and nodules ion his lungs. how do I stop crying.. how do I get him moving and not giving up?

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Things that have been approved immunotherapy in the United States are Opdivo which is the sibling of Keytruda. Like a male female relationship. This is one avenue to ask your doctor about. If they don’t offer much hope, there is a Dr Ralf Kleef in Austria who treats with immunotherapy combination drugs in reduced amount so that it is more safe.
In the meantime if you are being only told about chemotherapy, I would highly recommend learning about coffee enemas. They cause the liver to detox quickly. A liver can completely regenerate itself within 9 months. Also check out Chris Warks website Square One. It is a natural approach….. helping yourself in my opinion is using the best of both worlds. I do not agree with using traditional chemo with Stage 4 colon cancer as it is a very low success rate. Dr Kleef is an oncologist so he uses immunotherapy but he is integrative and also uses natural things like mistletoe and a unique treatment to I crease body temperature safely to kill cancer cells. Just know there is so much stuff out there. Stop all sugar that doesn’t come from fruits and vegetables in their natural form , stop all processed foods immediately. These are all my personal opinions and aren’t meant to be used as medical counseling, but so do want you to be aware of many things around you so that it isn’t cookie cutter treatment. Like I said the results for golfos and Folfuri in Stage 4 colon cancer speaks for themselves. I pray you have a chance to pray and seek Gods guidance for you and remember through faith you can be healed. The Bible says it and the Bible does not lie.

Liked by virgo1952

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@mdking123

Things that have been approved immunotherapy in the United States are Opdivo which is the sibling of Keytruda. Like a male female relationship. This is one avenue to ask your doctor about. If they don’t offer much hope, there is a Dr Ralf Kleef in Austria who treats with immunotherapy combination drugs in reduced amount so that it is more safe.
In the meantime if you are being only told about chemotherapy, I would highly recommend learning about coffee enemas. They cause the liver to detox quickly. A liver can completely regenerate itself within 9 months. Also check out Chris Warks website Square One. It is a natural approach….. helping yourself in my opinion is using the best of both worlds. I do not agree with using traditional chemo with Stage 4 colon cancer as it is a very low success rate. Dr Kleef is an oncologist so he uses immunotherapy but he is integrative and also uses natural things like mistletoe and a unique treatment to I crease body temperature safely to kill cancer cells. Just know there is so much stuff out there. Stop all sugar that doesn’t come from fruits and vegetables in their natural form , stop all processed foods immediately. These are all my personal opinions and aren’t meant to be used as medical counseling, but so do want you to be aware of many things around you so that it isn’t cookie cutter treatment. Like I said the results for golfos and Folfuri in Stage 4 colon cancer speaks for themselves. I pray you have a chance to pray and seek Gods guidance for you and remember through faith you can be healed. The Bible says it and the Bible does not lie.

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Folfox not golfos. It was spell corrected

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@mdking123

Things that have been approved immunotherapy in the United States are Opdivo which is the sibling of Keytruda. Like a male female relationship. This is one avenue to ask your doctor about. If they don’t offer much hope, there is a Dr Ralf Kleef in Austria who treats with immunotherapy combination drugs in reduced amount so that it is more safe.
In the meantime if you are being only told about chemotherapy, I would highly recommend learning about coffee enemas. They cause the liver to detox quickly. A liver can completely regenerate itself within 9 months. Also check out Chris Warks website Square One. It is a natural approach….. helping yourself in my opinion is using the best of both worlds. I do not agree with using traditional chemo with Stage 4 colon cancer as it is a very low success rate. Dr Kleef is an oncologist so he uses immunotherapy but he is integrative and also uses natural things like mistletoe and a unique treatment to I crease body temperature safely to kill cancer cells. Just know there is so much stuff out there. Stop all sugar that doesn’t come from fruits and vegetables in their natural form , stop all processed foods immediately. These are all my personal opinions and aren’t meant to be used as medical counseling, but so do want you to be aware of many things around you so that it isn’t cookie cutter treatment. Like I said the results for golfos and Folfuri in Stage 4 colon cancer speaks for themselves. I pray you have a chance to pray and seek Gods guidance for you and remember through faith you can be healed. The Bible says it and the Bible does not lie.

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@mdking123 interesting read. I was lucky with my colon re-section. Found early, no spread, so lost some length of my colon and my gallbladder. That was kind of a mystery. My surgeon didn’t say anything about removing my gallbladder. Learned it while in the hospital when the nurses were changing shifts and reporting to each other. I have since read that there is thought or a connection between re-occurring cancer and the gallbladder. Guess, he was just giving me a better outcome (?). I have always thought what you eat directly effects your body and quality of life. But cancer is abnormal cells and we are made up of cells. So, a clean diet and alternative methods can only go so far. I remember my Mom told me years ago anytime you mess with your natural rhythm, you will “pay the piper” down the line. Apparently, she was way ahead of her time and taught me a lot about food, lifestyle and taking care of myself (in general). I always think about what she said when I am making a health/medical decision. virgo

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@mdking123

Things that have been approved immunotherapy in the United States are Opdivo which is the sibling of Keytruda. Like a male female relationship. This is one avenue to ask your doctor about. If they don’t offer much hope, there is a Dr Ralf Kleef in Austria who treats with immunotherapy combination drugs in reduced amount so that it is more safe.
In the meantime if you are being only told about chemotherapy, I would highly recommend learning about coffee enemas. They cause the liver to detox quickly. A liver can completely regenerate itself within 9 months. Also check out Chris Warks website Square One. It is a natural approach….. helping yourself in my opinion is using the best of both worlds. I do not agree with using traditional chemo with Stage 4 colon cancer as it is a very low success rate. Dr Kleef is an oncologist so he uses immunotherapy but he is integrative and also uses natural things like mistletoe and a unique treatment to I crease body temperature safely to kill cancer cells. Just know there is so much stuff out there. Stop all sugar that doesn’t come from fruits and vegetables in their natural form , stop all processed foods immediately. These are all my personal opinions and aren’t meant to be used as medical counseling, but so do want you to be aware of many things around you so that it isn’t cookie cutter treatment. Like I said the results for golfos and Folfuri in Stage 4 colon cancer speaks for themselves. I pray you have a chance to pray and seek Gods guidance for you and remember through faith you can be healed. The Bible says it and the Bible does not lie.

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Immunotherapy is the use of medicines to help a person’s own immune system better recognize and destroy cancer cells. Immunotherapy can be used to treat some people with advanced colorectal cancer. Integrative medicine, which is a combination of medical treatments for cancer and complementary therapies to cope with the symptoms and side effects, is increasingly offered at premiere cancer centers around the world, including Mayo Clinic.

When considering complementary or alternative treatments, be open-minded yet skeptical and do your research. Learn about the potential benefits and risks. Here is an article from Mayo Clinic that might interest you about evaluating claims made by the producers and/or sellers of supplements, natural products and other alternative medicines. http://mayocl.in/2tGC0Jp

Here is just one article examining the claims made by Chris Wark:
– From Science Base Medicine https://sciencebasedmedicine.org/chris-beat-cancer-a-comprehensive-guide-to-making-a-killing/

"There’s no scientific evidence that proves or disproves that coffee enemas are helpful to treat any medical condition. Evidence for or against the use of coffee enemas is mostly anecdotal. In mainstream medicine, colon cleansing is considered unnecessary because your body’s digestive system is capable of getting rid of waste, toxins, and bacteria on its own."
https://www.healthline.com/health/coffee-enema

Liked by virgo1952

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@colleenyoung. I consider myself opened minded and have a holistic approach with treatments and lifestyle. I read the articles, learned from them. I hesitate to start practicing some of methods on my own. I think it can be detrimental to the bodies way of breaking down your foods and eliminating the waste. The body is an amazing thing, but I wonder if some of these treatments/methods create different problems; and, I don’t feel that exchanging one for another is something I want to do. It’s seems to always be a trade off, whether medically approved or not. It’s a gamble. But, each person needs to make his/her decision

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