I have been on one Rytary 48.75/195mg 4x’s per day for almost 3 years

Posted by sdblondie @sdblondie, Oct 14 5:09am

I barely notice I have PD when taking Rytary. The off periods were not even noticeable unless I went way late with a dose. Recently, I feel like it’s not helping like it used to. I originally took Sinemet, but it gave me nausea still after several weeks.
How long have you gone before you needed to up dosage?
I have traveled a lot over the years and I’ve started having problems after returning home from trips. I get nausea, tingling in my fingers and toes, terrible anxiety, vomiting (I know, crazy) loss of appetite and have ended up in ER twice. I’m released after hydration, blood work and usually Ativan to calm me down. I have NEVER gone to ER in my life except when I was in labor. My husband is very worried and says he doesn’t recognize me when we are at the ER. He says he tells doctor and nurses that this absolutely not me.
I also started having low blood pressure and was taken off BP meds with no problem. I was diagnosed in 2021 and 72 yrs old. Until recently, I’ve been active, swim a few times a week, ride my 3 wheel trike, participate in lots of family activities, etc.
I’m getting paranoid about traveling and afraid I’ll never return to my old self

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Hello @sdblondie and welcome to Mayo Connect. I have requested that your post be moved to another Connect discussion on Rytary,
--Is anyone using Rytary?
https://connect.mayoclinic.org/discussion/is-anyone-using-rytary/
My first thought is whether you have consulted with your PCP regarding these post-travel symptoms. If not, this might be a good first start. I would like to hear from you again as you seek answers for this problem. Will you continue to post?

REPLY
@hopeful33250

Hello @sdblondie and welcome to Mayo Connect. I have requested that your post be moved to another Connect discussion on Rytary,
--Is anyone using Rytary?
https://connect.mayoclinic.org/discussion/is-anyone-using-rytary/
My first thought is whether you have consulted with your PCP regarding these post-travel symptoms. If not, this might be a good first start. I would like to hear from you again as you seek answers for this problem. Will you continue to post?

Jump to this post

I have a call into my MDS and PCP today. I think it’s more than Rytary issues. PD has so many other facets to it. I’m even investigating Parkinson’s Gastroparesis since my symptoms mirror many of those and are so random. The anxiety, vomiting are perplexing, but not uncommon to PD. I’m hoping others can be of help! Thanks!

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