time to decide and I'm stuck....
PSA: 9 ng/mL
Prostate size: about 30 cc (MRI 3.3 × 4.2 × 4.1 cm)
Gleason score:
One core: 3 + 4 = 7 (Grade Group 2, favorable intermediate risk)
Seven cores: 3 + 3 = 6 (Grade Group 1, low risk)
Positive cores: 8 of 12
I'm considered favorable-intermediate risk, I have the option of radiation (inter or external) and surgery. I think I've reached the point of information overload. The RO called and wanted to proceed after reviewing my PET and MRI. I told them I need some time. I like the idea of eliminating the cancer by getting the prostrate removed, I'm not looking forward to staying in the hospital, going under the knife, wearing a catheter for a week, and when the doc said he was gonna pull back (my little friend, lol!) that gave me some pasue as well.
I've reached an impasse. while I like the idea of getting rid of the prostrate to get rid of the cancer, with surgery, but the physical side effects don't appeal to me. Radiation is appealing but I do fear the long-term effects.
This is what understand
surgery: immediate side effects
radiation: gradual long-term effect develop over time.
Is it safe to say regardless of the treatment it come down to do I want to physical side effects up front or roll the dice that I may not develop long term effects due to radiation exposure.
how did you decide?
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mahnenrl, you can work and drive. Radiation treatment is painless. It can cause fatigue and you may need a little extra sleep. I wonder though if a different form of radiation treatment might easier on you. There is a five session treatment https://www.youtube.com/watch and have you looked at focal treatments https://www.youtube.com/watch
Best wishes for successful treatment.
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1 Reaction@mahnenrl
What I can to is give you my personal experience but I don't think I or anyone else can tell you what you can do or not do as we are all different.
1. Still able to work: I was retired when I got my 30 rounds of radiation but was avid exerciser. I exercised every day 1-2 hours.
2. Driving: Yes you can drive unless told not to. Are you taking a hormone? I drove 1 hour to my treatments and 1 hour back. Other than trying to schedule your trips to bathroom should be able to drive. For me I had to consume 16 oz. of water prior to treatments so waiting to do that until got there. Then made sure I used the bathroom prior to driving home. You mentioned fatigue I had it so minor but if yours affects you talk to your doctors.
3. Fatigue common: Yes but for me it was very minor. It did not stop my from exercising every day. But I could notice I was a little more tired when I did. Again I will asked if you are going on hormone treatments. I was not on hormones. It can have dramatic affects on some.
What was your Gleason score? Did you have tests like Decipher, PSMA? I mention those as I had them to help me and my doctors find the best treatment for me. Did your R/O discuss having the Space/Oar to help move colon away from prostate. How about drinking water prior to treatments to move bladder away from prostate.
I was 76 when I had my radiation treatments. Staying active, eating well, taking your vitamins and supplements (check with your R/O about taking any vitamins and supplements), and try to stay active.
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4 Reactions@gently , thank you, I will discuss with RO
@jc76 - thank you - yes I will have Spacer inserted - Did not have Decipher PSMA tests.
To all who keep seeing my same post: my apology, but...with each newly diagnosed person who has joined this blog, I must say:
The Gleason Score is only the "tip of the iceberg"...what could be and usually is, a huge iceberg of unknown pathology lurking under the waters unseen, until you have the radical prostatectomy. I too was a Gleason 3 + 4 = 7 with only 6-10% of cells being classified "4". I had 3 negative/normal cores, 3 cores 3 + 3 = 6, and 6 cores 3 + 4 =7. My urologist was confident ("we caught this early."), but still insisted on the radical prostatectomy. He does not believe in "Active Surveillance" ("You HAVE cancer, it is not going away, and why give it two years to get worse?"). So...I am glad I had the radical prostatectomy because...
I had all kinds of additional pathology that a biopsy and Gleason Score can't reveal. It threw me from what was thought to be a T1, or at worst a T2, class cancer, to a pT3b cancer because I had Extraprostatic Extension (the tumor broke through the membranous capsule that surround the prostate). With that, all bets are off. Thus, I had "surgical margins" showing that the tumor extended beyond what the urologist removed from me. In other words, he left cancer cells in me. And...the pT3b means that the cancer invaded one or both seminal vesicles because it broke out of the capsule. I had left seminal vesicle invasion...fortunately without tumor or nodules - just cells at that point. I also had Cribriform glands tissue...another ominous sign.
What I am getting at, is that the Gleason Score just tells you that have, or don't have, cancer, and if you do, the cellular characteristics allow a classification. But...it says nothing of what is going on anatomically with the growth and spread of the tumor. My advice is to have the radical prostatectomy AND make sure that you get the Decipher Test. It is a proprietary test developed and performed only by Veracyte Labs in San Diego, CA. It is a test that screens for 22 known prostate-specific genes, and it yields a test result "score" of 0.1 - 1.0. You want a low score showing you don't have any of the genes, or if you have them, they aren't the worst genes. The closer you are to the 1.0, the more genes you have, and which are the worse genes to have. The score yields a risk-stratified prediction of metastasis and your mortality (longevity) at 5 years, 10 years, and 15 years with standard therapy and treatment. Make sure your urologist sends some of your biopsy or post-surgical tissue to Veracyte Labs for that test. Bottom line: Like me, you can have a seemingly low-moderate risk cancer based on the Gleason Score, when in reality, your cancer can be more aggressive and far worse. Good luck to you.
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5 Reactions@rlpostrp
My situation is similar and I agree with all of rlpostrp comments. My second opinion biopsy came back GLEASON 9, the primary was GLEASON 8. Seeing the difference between one lab reading and the other helped me to decide yes for the prostatectomy. The post surgery pathology showed positive margins, seminal vessel invation and cribiform. I am very relieved that I chose the prostatectomy. Since then I've had salvage radiation, two additional targeted rounds of radtion on lymph nodes. Plus three cycles of ADT, currently on Orgovyx. Knowing exactly what was going on pathologically was a big help for me to feel confident I'm doing all I can to manage my prostate cancer.
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3 ReactionsThanks for the comments. I have a few questions:
1. What was your pre-surgical PSA level?
2. What were your post-op PSA levels and how long after surgery was it that prompted the radiation therapy...or was it proactive on the assumption your cancer would return since you have position surgical margins and seminal vesicle invasion?
3. You must have been a pT3b like me due to seminal vesicle invasion. What was your Decipher Test score...did you have that test done? Good luck to you.
@mahnenrl, how are your radiation treatments going? Are you able to continue working? Do you feel comfortable driving?
From my view it is cancer with an eventual earlier death without treatment or treatment with the inconvenience of side effects that offers a chance of more years of life. RP one week with a cath, one night in the hospital and a few months strengthening pelvic floor was my experience. After 5 months I no longer wore a pad. Easy to deal with. But then 2 years later BCR and salvage radiation which I finished a year ago.
In my case I've had many more continuing and increasing side effects from radiation than the RP. Currently being treated for radiation proctitis. A friend of mine choose radiation for his first treatment due to knowing so many others that had an RP followed by radiation due to cells left in the pelvic area. Another friend chose proton and so far very mild side effects. 50 sessions with a total of 3 hours of driving to get to the center daily. All are feeling hopeful about their ongoing lives. Paralysis analysis is a real thing.
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