What vitamins to avoid when taking Hydrea (hydroxyurea) for ET JAK2?

Posted by lindagualtieri @lindagualtieri, Feb 20 6:28am

I currently have essential thrombocythemia with the JAK2 gene mutation. I currently take 500 mg of hydra seven times a week. I’m supposed to take two doses three times a week which I’m not doing any longer because my platelet counts have fallen back to 418. What kind of vitamins should you avoid while taking hydra i.e. multivitamins vitamin D vitamin K etc. has anyone had any issues with taking vitamins with this chemo drug?

Interested in more discussions like this? Go to the Blood Cancers & Disorders Support Group.

nande | @nande | Feb 20 7:11am

Hi,
I started Hydrea 9 months ago.
I take vitamin D, vitamins B, Biotin, and vitamin C when needed.
I haven’t had any reactions from the vitamins with Hydrea.

skossaz | @skossaz | Feb 20 9:09am

I take vitamin D and K 5000
mg and folic acid 1 mg
While taking hydroxyurea 500 1 5days a week and 2 tablets Saturday and Sunday. Ok by cancer doc and I have ET also with Jak 2 mutation for the last year and one-half. I am 86 years old .

janemc | @janemc | Feb 21 7:11am

On HU since October 2023, I also take a multivitamin, an AREDS vitamin to protect vision, and a calcium/vitamin D supplement for my bones. I'm a 71 year old woman with ET, MPL mutation.

My oncologist has no objections to those supplements.

We are all different, though! It's always best to ask your doctor what's OK for you.

nohrt4me (Jean) | @nohrt4me | Feb 21 8:57am

During COVID, oncology suggested a multivit as a way to boost immunity. (This was before the COVID vax was available.) I was taking hydroxyurea at that time. No problems, so I kept taking my multivit.

I did go off the multivit between blood checks (every three months). Going off the multivit made no diff in labs this month, so I went back on them. They seem to improve energy a bit.

ebertolis | @ebertolis | Feb 21 9:30am

I take Hydrea (2x500g a day) and also vitamin D, Bluberry pills for eyes and Berberine (this every second day). I would not take Biotin, for my kidneys are in insuffisance (Dfg 59).

vickieannb57 | @vickieannb57 | Feb 21 11:18am

Oncology Doctor has me on Iron and B12 I also take Biotin and a Super B complex. Take Hydra 500mg x 7 daily. Along with my other medications I think the iron gives me issues but usually after breakfast but only for the first hour of the day I take the iron on an empty stomach.

betty82 | @betty82 | Feb 22 10:16am

In reply to @skossaz "I take vitamin D and K 5000 mg and folic acid 1 mg While taking hydroxyurea..." + (show)

@skossaz I have ET also with Jake 2 I’ve been on hydro 500mg everyday for one year this month, I take vitamin B12 also folic acid and magnesium. I am 85 years old.

zmg | @zmg | Feb 22 1:07pm

In reply to @nande "Hi, I started Hydrea 9 months ago. I take vitamin D, vitamins B, Biotin, and vitamin..." + (show)

@nande Hi!
That’s a question that I plan to ask my hematologist when I see him next month. I am on Hydro, 500 mg daily, my platelets are at 345, so I hope I can maybe reduce the dosage to take a pill every other day. I wonder if taking a vitamin supplement would help with the fatigue I am experiencing after being on the medication!
Anyone feeling better after starting taking a multivitamin??
Thank you!!

janemc | @janemc | Feb 23 4:45am

In reply to @zmg "@nande Hi! That’s a question that I plan to ask my hematologist when I see him..." + (show)

@zmg

Please see nohrt4me's helpful comment on multivitamins by scrolling up a few posts . . . .

beauty44 | @beauty44 | Feb 23 2:16pm

In reply to @vickieannb57 "Oncology Doctor has me on Iron and B12 I also take Biotin and a Super B..." + (show)

@vickieannb57
Hi
Does your Dr tell you to take iron on an empty stomach ? It can be tough on the stomach.
We all keep on and trying to do what is best for our lives.
You’re doing well and keep strong. Blessings every day
Donna

View More View Less

Please sign in or register to post a reply.