Mayo Clinic Connect
I completed all treatments for breast cancer but now I am supposed to take hormone blocker, named anastrozole. im concerned about the side effects. Has anyone here taken it and did anyone have hair loss?
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Elizm, I had the oncotype (low score) which as I understand showed that chemo was not necessary. What did you learn from the Mammoprint?
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It's was the MammaPrint 70-Gene Risk of Recurrence which essentially told me that I was at high risk for recurrence within 10 years without chemo and hormonal therapy. As I recall, it's the report for those who are ER+. There's a secondary report which financially is separate — BluePrint 80-Gene Molecular Subtype — which my oncologist did not request.
@elizm what is the difference? Why would one be viable vs the other? I had oncotype and my number was 19 and found the RAD51C mutation. Thus oophorectomy / hysterectomy and 20 radiation treatments
Gwinter. Google does a better job than me explaining the difference
A year-and-a-half ago, I might have remembered the differences, but I think it has to do with whether you're ER+ or ER-. I also noted that, on the Mammaprint report, it was noting some stats for those who are HER2-, and I'm HER2+….
Elizm, did you also have the oncocyte test?
As noted earlier, I believe that the OncotypeDX is only viable for those who are ER- (and I'm ER+).
No I was ER+ and had the oncotype test. I was a 22. So based on that, (middle range result) then chemo does not improve the survival rate.
Hi. I don't want to appear dumb but what is an oncotype test and how do you know if you had one? I was er+ as well.
You're not at all dumb. Some of us panicked when told that part of the treatment plan was chemo… and these tests potentially can tell you that you're a good candidate (because of high rate of recurrence) or not to have the chemo. They basically test a sample of your tumor (following lumpectomy or mastectomy) for various genes.
Liked by Colleen Young, Connect Director
Thank you Elizm. I've just completed chemo and radiation a month ago so was a bit confused.
@karendb – Karen, you are not dumb! There is so much technical information that happens plus the emotional side of your diagnosis. It's truly awesome we have this group to help us understand and to give support.
Liked by Colleen Young, Connect Director, lisman1408
@sparklegram, thank you.
It is a gene test of your particular tumor. It has a score of 1 to 50. if your score is low 26 then you do need chemo, in the middle was a "grey" area. I was a 22, IN June of 2017, they released a 10 year study of 8,000 women. Based on that study the Middle range, doing chemo for them, did not improve their survival rates. Since I was in the middle at 22, my oncologist said I did not need chemo. Previous to the study, I would have under gone Chemo. Since you had chemo already, I guess either you had the test or your doctor just decided you should take it. Anastrozole is a Form of chemo – by suppressing Hormones, it reduces the chance your tumor will re-occur. I agree more information helps us all.
Thank you kathyomaha55.
All, If you had to choose between Aromasin or Arimidex, which would you choose and why (focusing on side effects)?
@francine6829, I've been on arimidex for about a month now and have just noticed a few aches and a bit of insomnia. I hope this is as bad as it'll be cause 5 years seems like such a long time to have to take it.
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