Concerned about the side effects of anastrozole

Posted by tinalove @tinalove, Jan 31, 2016

I completed all treatments for breast cancer but now I am supposed to take hormone blocker, named anastrozole. im concerned about the side effects. Has anyone here taken it and did anyone have hair loss?

@francine6829

Elizm, I had the oncotype (low score) which as I understand showed that chemo was not necessary. What did you learn from the Mammoprint?

Jump to this post

@francine6829 @kathyomaha55
It's was the MammaPrint 70-Gene Risk of Recurrence which essentially told me that I was at high risk for recurrence within 10 years without chemo and hormonal therapy. As I recall, it's the report for those who are ER+. There's a secondary report which financially is separate — BluePrint 80-Gene Molecular Subtype — which my oncologist did not request.

REPLY
@gwinter

@elizm what is the difference? Why would one be viable vs the other? I had oncotype and my number was 19 and found the RAD51C mutation. Thus oophorectomy / hysterectomy and 20 radiation treatments

Jump to this post

Gwinter. Google does a better job than me explaining the difference

REPLY

@gwinter
A year-and-a-half ago, I might have remembered the differences, but I think it has to do with whether you're ER+ or ER-. I also noted that, on the Mammaprint report, it was noting some stats for those who are HER2-, and I'm HER2+….

REPLY
@elizm

@francine6829 @kathyomaha55
It's was the MammaPrint 70-Gene Risk of Recurrence which essentially told me that I was at high risk for recurrence within 10 years without chemo and hormonal therapy. As I recall, it's the report for those who are ER+. There's a secondary report which financially is separate — BluePrint 80-Gene Molecular Subtype — which my oncologist did not request.

Jump to this post

Elizm, did you also have the oncocyte test?

REPLY
@francine6829

Elizm, did you also have the oncocyte test?

Jump to this post

@francine6829
As noted earlier, I believe that the OncotypeDX is only viable for those who are ER- (and I'm ER+).

REPLY
@elizm

@francine6829
As noted earlier, I believe that the OncotypeDX is only viable for those who are ER- (and I'm ER+).

Jump to this post

No I was ER+ and had the oncotype test. I was a 22. So based on that, (middle range result) then chemo does not improve the survival rate.

REPLY

Hi. I don't want to appear dumb but what is an oncotype test and how do you know if you had one? I was er+ as well.

REPLY

@karendb
You're not at all dumb. Some of us panicked when told that part of the treatment plan was chemo… and these tests potentially can tell you that you're a good candidate (because of high rate of recurrence) or not to have the chemo. They basically test a sample of your tumor (following lumpectomy or mastectomy) for various genes.

REPLY
@elizm

@karendb
You're not at all dumb. Some of us panicked when told that part of the treatment plan was chemo… and these tests potentially can tell you that you're a good candidate (because of high rate of recurrence) or not to have the chemo. They basically test a sample of your tumor (following lumpectomy or mastectomy) for various genes.

Jump to this post

Thank you Elizm. I've just completed chemo and radiation a month ago so was a bit confused.

REPLY
@elizm

@karendb
You're not at all dumb. Some of us panicked when told that part of the treatment plan was chemo… and these tests potentially can tell you that you're a good candidate (because of high rate of recurrence) or not to have the chemo. They basically test a sample of your tumor (following lumpectomy or mastectomy) for various genes.

Jump to this post

@karendb – Karen, you are not dumb! There is so much technical information that happens plus the emotional side of your diagnosis. It's truly awesome we have this group to help us understand and to give support.

REPLY
@sparklegram

@karendb – Karen, you are not dumb! There is so much technical information that happens plus the emotional side of your diagnosis. It's truly awesome we have this group to help us understand and to give support.

Jump to this post

@sparklegram, thank you.

REPLY
@karendb

Thank you Elizm. I've just completed chemo and radiation a month ago so was a bit confused.

Jump to this post

It is a gene test of your particular tumor. It has a score of 1 to 50. if your score is low 26 then you do need chemo, in the middle was a "grey" area. I was a 22, IN June of 2017, they released a 10 year study of 8,000 women. Based on that study the Middle range, doing chemo for them, did not improve their survival rates. Since I was in the middle at 22, my oncologist said I did not need chemo. Previous to the study, I would have under gone Chemo. Since you had chemo already, I guess either you had the test or your doctor just decided you should take it. Anastrozole is a Form of chemo – by suppressing Hormones, it reduces the chance your tumor will re-occur. I agree more information helps us all.

REPLY
@kathyomaha55

It is a gene test of your particular tumor. It has a score of 1 to 50. if your score is low 26 then you do need chemo, in the middle was a "grey" area. I was a 22, IN June of 2017, they released a 10 year study of 8,000 women. Based on that study the Middle range, doing chemo for them, did not improve their survival rates. Since I was in the middle at 22, my oncologist said I did not need chemo. Previous to the study, I would have under gone Chemo. Since you had chemo already, I guess either you had the test or your doctor just decided you should take it. Anastrozole is a Form of chemo – by suppressing Hormones, it reduces the chance your tumor will re-occur. I agree more information helps us all.

Jump to this post

Thank you kathyomaha55.

REPLY

All, If you had to choose between Aromasin or Arimidex, which would you choose and why (focusing on side effects)?

REPLY

@francine6829, I've been on arimidex for about a month now and have just noticed a few aches and a bit of insomnia. I hope this is as bad as it'll be cause 5 years seems like such a long time to have to take it.

REPLY
Please login or register to post a reply.