How is it that a person can be allergic to insulin when your body prod

I’m not sure of the scientific explanation, I only know that I am allergic to Lactose, and it is used in medicines as fillers and binders. I have 1 injectable medicine for my T2D, that I can tolerate, Ozempic. (I have a low tolerance for most medicines). You might want to check out an allergy connection. If I cannot find the formulary thru the internet, I have a college in my town with a pharmacy program, and I can ask them for research help. They’ve been very helpful.
Best wishes.

@angelamc69 May I ask if it is you having this difficulty, or someone you know?

I am asking because a person with diabetes can respond very differently to different types of insulin. The "human" (i.e. manufactured) insulins can be made from different bacteria, so I suppose that a person could be allergic or sensitive to a specific one. In addition all insulins, human & animal, contain different preservatives, to which some people may be allergic or sensitive.

But beyond allergy, it can take a long time to hit on the best individual product - it may be animal or human, long-acting or short-acting, different brand or dosage... In the meantime, the person can feel very bad, with spikes and low values in blood sugars, headaches, fatigue, body aches and no energy. That is why it is very important for patient and doctor to work as a team to find the right combination of diet, insulin and activity.

Sue

Yes, it is me. I have had diabetes for over 20 years and have tried, I believe, just about all insulin. They either make me itch or worse. This last one I just tried, (Toujeo) most likely triggered Respiratory Acidosis. I am also allergic to Estrogens in which the body produces. My diabetes has never been controlled, even after losing 125 pounds.

I am severely allergic to sulfa (anaphylaxis). I think some insulin may contain it. I have had diabetes over 20 years and have tried many.

There is at least one preservative-free insulin - Myxredlin.
Also, for several months I had to take an antibiotic that made me itch and blistered my skin. There was no viable alternative for the infection I had, so I took a dose of Benadryl (antihistamine) with each pill.

If neither of those is an option for you, perhaps you need to seek treatment at a clinic or hospital known for handling difficult cases of diabetes?
Sue

I have thought about it. Thank you.

I think someone may have touched on this but insulin used to be derived from beef and pork. After that it was genetically engineered to mimic human. Still there may be fillers, binders, preservatives and additives of all kinds. Do you have a medical provider taking care of your allergies who can collaborate with the provider that prescribes your insulin? Maybe they can both work together with you to find what may work best.

I do not have an allergist. But I will get one and hopefully get this under control. Thank you.

Thank you.