Hormone therapy before radiation treatment question....

Posted by lg22222 @lg22222, 1 day ago

Hello teammates...
I was diagnosed with prostate cancer at age 65. PSA results were elevated at 12.5....Had the MRI's and biopsy done as well...
PiRads of 5....Biopsy shows Gleason scores of 7 (4+3) and Stage 2 unfavorable...
After much research and meetings with radiation oncologists and surgeons, i decided to go with radiation. I am lucky that living in the NYC metro area I am able to work with NYU Langone. I will be getting treatments with the MRI Linac machine.
The Dr recommends 6-8 weeks of daily ADT treatments (pill) prior to radiation...
My question is this....what should I be doing to prep for the hormone treatments from a diet point of view...I do walk 3-5 miles a day (weather permitting) and train with kettle bells.
I am concerned about muscle loss, heart and bone issues, and some of the other potential side effects. I know we are all different in what we can tolerate, but I want to make sure I am prepared as best as I can before I enter the ring and deal with the ADT and radiation treatments.

Thank you for any comments and assistance in this matter.....

PS: Sorry if I didn't include any other pertinent info....I am a rookie to this forum...Thanks for understanding

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for jeff Marchi @jeffmarc

@ecurb
While you suffer from fatigue, be careful about how much sleeping you do in the afternoon. I occasionally get tired in the afternoon, I take a 25 minute nap setting my phone for 25 minutes. That keeps me awake till midnight.

The problem is, if you sleep more than about an hour, you go into REM sleep. Once that happens it makes it more difficult to sleep at night. People find they’re not getting a full nights sleep when they do that, and as a result, they are tired in the afternoon. The short naps resolve that issue and allows you to get a full night’s sleep.

Jump to this post

@jeffmarc you are correct. Won’t argue with that. Otherwise I get the privilege of tossing and turning all night between bathroom trips. Good advise.

REPLY
Profile picture for jeff Marchi @jeffmarc

If he wants you to take a daily ADT, then he probably is going to give you Orgovyx, The only ADT you get daily. Orgovyx For ADT Allows the testosterone to come back much quicker, which will minimize the side effects.

While you will have some effects from the ADT. They should be very short term. Muscle loss bone deterioration are all things that happen over time not enough matter of a couple of months. You could do some weight exercises to keep the muscles you have in shape.

Whether or not you gain weight is up to you most of the time. Weigh yourself on the scale daily and eat based on what you weigh. I’ve never gained weight and I’ve been an ADT for eight years.

You may get hot flashes. If you do, there are some resolutions, Come back and ask if you have a problem with them.

3 1/2 years after my surgery, my PSA started rising, so I had salvage radiation. They gave me a six month Lupron shot two months before the radiation. To tell you the truth, I didn’t really have any side effects at all from it. He’ll be much better off with Orgovyx.

Recent studies I’ve shown it’s more effective to have ADT at the time of radiation Or shortly after it rather than Before radiation. Here’s some information about that you could talk to your doctor about. This is pretty new information and doctors are not really doing it yet.
https://www.medscape.com/viewarticle/940049
Some information on radiation treatment, if you’re cancer comes back.
People who have radiation as their primary treatment have been told by doctors that surgery isn’t really an option if there’s a reoccurrence. Other options are not really mentioned..

This study shows that both salvage focal therapy (HIFU and cryotherapy) and salvage surgery were equally effective at extending the life of a patient that started off with radiation.

Those that had focal therapy had fewer perioperative complications.
https://jamanetwork.com/journals/jamaoncology/article-abstract/2844900
.

Jump to this post

@jeffmarc

Thank you so much for the information and links....I am so glad I found this group.....Everyone has been very helpful, and I am learning by everyone's responses, and comments throughout this board....

I received an update from NYU today as well....They sent my biopsy slides to a company in Florida (Artera) which does an AI assessment of the biopsy slide...My prognostic risk score was "low"...And the document mentioned "no clear risk reduction with the addition of short-term androgen deprivation therapy to RT"...

The great staff at NYU believes with my advance PC, I should still follow through with the short term ADT. It's because the pathologist noticed cribriform when they reviewed the slides....I am waiting for the Decipher results which won't be ready for 4-5 days....

The nurse practitioner did mention to me that the ADT treatments will be for 4-6 months, and not 4-6 weeks.....I guess I misunderstood when I met with the RO at NYU....either way I am preparing myself mentally and physically for the journey ahead....

I really appreciate all the guidance and support from ya all.....

You all are in my prayers!

Thank you!!

REPLY
Profile picture for heavyphil @heavyphil

You will probably continue ADT for 6-8 weeks after radiation as well; it’s usually a 6 month total, but 4 is also done.
Keep exercising -especially when you don’t feel like it! Pushing thru the fatigue is KEY for success.
Also, get your body used to low fiber meals - gas in the bowels is a big no no! The Linac machine is great when it comes to thus because it automatically turns off if a gas bubble moves your prostate out of target range; but your RO won’t be happy if the 15 minute procedure becomes an hour or more because of gas issues. Do some diet homework! Best,
Phil

Jump to this post

@heavyphil

Thank you so much.....

You are correct regarding the ADT treatments continuing for 6-8 weeks after radiation....I received a call today from NYU stating that ADT treatments are 4-6 months....not 4-6 weeks like I thought.....

REPLY
Please sign in or register to post a reply.