High PSA Levels: What is the cause?
I have been fighting raising psa levels for past two yrs now. My urologist has done several psa and testostrone test done for possible ED problem . My first test was like at 7 or 8 when it is suppose to be between 0 and 4. He checked prostate and found it is enlarged . So he keeps monitoring psa. Still having sexual problems refering to ED. Test again before next appt . On appt date test was 12 for psa testostrone was like 200. He recomeded biopsy to check for prostate cancer so he did a ultrasound biopsy. Results neg for cancer. Has me test again before next visit psa 14 testostrone 192. He then tries some testostrone injections to bring up testostrone levels to try to help sexual problem test before appt psa slightly elevated testostrone 406. Still sexual problems so he sends me in for MRI to verify for sure i Dont have prostate cancer. Results still neg . Got frustrated no answers doc will not give me any meds to bring down my numbers. So he put me on bi mix injections to help with ED. Tries it out on me first then sends me home to suffer with a 6 to 7 hr errection and had to go back for emergency drainage of blood to bring it back down . Now really having ED problems even with bi mix prescription . Went back for test again psa 18.1 testostrone 204. Now he still refuses to give me meds to bring numbers down . Mri results found no sign of cancer they just showed i had a enlarged prostate. Which we already knew. Is my numbers going to keep going up and still test neg for cancer? What can i expect can the numbers just be high due to prostate enlarged and never have cancer? Where do i go next? What do i do next to get answers
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Biopsy completed. 6mm Adenocarcinoma, 4+4=8, Grade Group 4 40% of core, tow additional Adenocarcinomas 3+3=6 Grade Group 1 (both 1mm), one focal High Grade Prostatic Intraepithelial Neoplasia Grade 3, and One Focal Prostatic Intraepithelial Neoplasia Grade 3. Any thoughts on this?
prostate biopsy on Feb. 15th. Thanks Colleen for the above post and referenced articles. urinalysis was normal. Had TURP procedure done in 2014.
Welcome @sanabuju82. Rising PSA levels can be alarming. It may or may not be cancer. It's good that this is being followed and that you are having a biopsy.
Your question is a common one. So I moved your post to this existing discussion:
– High PSA Levels: What is the cause?: https://connect.mayoclinic.org/discussion/high-psa-levels/
I did this so you can read previous helpful posts and connect easily with members like @harley52 @legendts @jenatsky @kw070707 @rfherald and others.
Here's an article from Mayo Clinic about what to expect for the biopsy.
– Prostate Cancer Biopsy https://www.mayoclinic.org/tests-procedures/prostate-biopsy/about/pac-20384734
And two discussion where men who have had a prostate cancer biopsy share their experiences and tips:
– Anyone have an Ultrasound-Guided Transperineal Prostate Biopsy? https://connect.mayoclinic.org/discussion/anyone-have-an-ultrasound-guided-transperineal-prostate-biopsy/
– Prostate transrectal biopsy https://connect.mayoclinic.org/discussion/prostate-transrectal-biopsy/
When will you have the biopsy? Do you know which kind?
In August '21, psa 2.71; Oct '22, PSA 3.40 and in Jan.'23, 4.38. Scheduled for biopsy next week. Mildly enlarged prostate. From what I've read, this velocity is pretty aggressive. Does this lean toward one outcome or another? Thanks!
Hi Matt, what M.D did you see at Mayo?
Previous posters have reported an elevated PSA. Has anyone had a PSA that varies?
A biopsy was clean on eleven samples and 5% prostate cancer on the twelfth. MRI was clean. Is a second opinion suggested?
Anyone might know what's going on?
Hi, as a nurse, I suggest going for a secondary opinion. Bring all your records or have copies sent to the secondary opinion. Better to go to a Medical Center. Most have Nurse Navigators that can suggest the most appropriate M.D
If you’re unhappy with your treatment get another doc if possible. Out of curiosity when did you last have a complete physical by your PCP in consideration of another underlying cause?
Welcome @kw070707. That sounds like a long time to have fluctuating and high PSA counts and starting at a young age. Have your doctors ever explained why?
Hello I'm new to this group your systems are the same thing I'm going through I have PSA of a 20.I always had problems sense I was 30 years old I am 56 . DR gave medication for UTI for ten days that helped some went back last Thursday for another PSA .I had a rough day Thursday felt swollen and pain the hip area. The last three days been good what helps me is to drink lots of water I work outside if I get dehydrated that's when it will get worse