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High ISOPSA and PSA score?

Posted by careyp @careyp, 3 days ago

I just got my ISOPSA score of 7.7, 1st time and my PSA score that went up from 5.9 to 8.8 in a month. Waiting on my MRI results that I had taking with and without contrast. Spent collectively 43 years in the fire service. I was already beat up orthopedically. Wondering how concerned I should be with these numbers…

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careyp | @careyp | 3 hours ago
In reply to @jim18 "@careyp Concern should be on family history. One first degree (father, brother) male relative with prostate..." + (show)
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@careyp Concern should be on family history. One first degree (father, brother) male relative with prostate cancer doubles the risk that you will have prostate cancer.
If the MRI shows some PIRADs of 4 or 5 that also points to likely cancer. PIRADs 2&3 can be but usually are not (< 1/3) cancer. PSA can change up to 20% depending on lab methods. If the PSA has shown a steady increase over the last 6 years, there is a good chance that there is at least low-grade cancer. Was the 8.8 reported with the ISOPSA (these tend to be on high side) or done at the same lab as the 5.65? Sex or bike riding within 48 hours before the test also increase PSA.

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@jim18
1st thanks for your response.
The Total PSA of 8.8 did come as result of the ISOPSA. My family history and my work history have an extra layer of concern. In 1994 it took roughly 60 firefighters to extinguish a rubber factory fire after 4 days using AFFF foam from an airport crash/fire/rescue rig to finally get the fire out. Of just some of who we
knew was on the fire 9 guys got some form of cancer with 8 passing. No one can pinpoint that this was, or was just being a firefighter the connection. There’s a class action lawsuit against Monsanto for firefighting foam and for the flame retardant used in the protective properties of our gear. So all of the above just makes me extremely concerned because every aspect of potential exposure, whether family or career raises my concern factor. I have recently had to 2 fecal exams come back with blood in the sample that was not visible to the naked eye and I was diagnosed with Barrett’s esophagus. I failed a life insurance exam with CEA level of 5. I haven’t been able to track down the cause for that yet. And no sexual activity or bike riding, to orthopedically messed up for those activities…
Thanks again 🙏,
Carey

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dhasper | @dhasper | 2 hours ago

This period of time was really difficult with the anxiety. I am in the middle of recurrence and find this much less stressful than the original dx process. A good friend quoted me the Eagles "don't let the sound of your own wheels drive you crazy". Really good people here. Hope for the best and plan for the worst. You are already at an advantage seeking information here.

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