High Cobalt Chromium levels

Posted by windy77 @windy77, Aug 21, 2025

I have a MOM THR in 2003 - Depuy Pinnacle . I'm now 70. While I knew about potentials of Metalosis, I never had any symptoms so I was never tested. Jan 2024 my hip squeaked for a week, then went away. I'm very active and no weakness or other symptoms. I went to a recommended Ortho in Chicago area - since my original surgeon retired. I was tested and Cobalt/Chromium came back 22.6/15.5 ng/mL. I also had a MRI - which showed no abnormal issues. The decision was to wait a year and test again - which I did this month- the Cobalt/Chromium came back 11/11 ng/mL. - the results went down(both were done at the same lab in NC (lab corp of america). Still no other symptoms and squeaking never came back. I haven't met with my doctor again yet - presuming we'd do a wait another year plan again. I have several questions 1) Is it logical that my Cobalt Chromium went down - without doing anything? 2) Does it matter where blood tests are done? 3) Can other things affect blood tests - I don't take any medications. And stopped my Vitamin D the week before the blood test.

Interested in more discussions like this? Go to the Joint Replacements Support Group.

Profile picture for Hurkey @hurkey

@closer0043 I have a question if you don’t mind. Have you succeeded in keeping your cobalt and chromium levels down by taking NAC? Or did you have to pursue other methods?

Jump to this post

@hurkey I also found a multivitamin without chromium in it. It’s a company called ritual. Pretty basic ingredients.

REPLY
Profile picture for closer0043 @closer0043

@hurkey Sorry I haven’t tested them since they went down originally after taking NAC for just a few weeks. I was recently diagnosed with an ascending aortic aneurysm, and that issue has dominated most of my concern these days. Plus, the lab that I used for testing has recently closed and moved an hour and a half away so I’m looking for a new lab. My doctors won’t test me since my numbers were never that high. According to my original test my chromium was 2.0 and cobalt 2.4 with normal being under 1.2 & 1.8. After just a few weeks the chromium went down to 1.7 & Cobalt dropped to normal at 1.5. If I test again I will update this post.

Jump to this post

@closer0043 I’m sorry to hear of your aortic aneurysm; yes I can imagine that does keep you occupied. Thanks for responding. From all I’m reading at those lower levels you’re not in danger unless you have pain or trouble with the hip, or erosion is seen in an image. I wish you the very best!

REPLY
Profile picture for closer0043 @closer0043

@hurkey Sorry I haven’t tested them since they went down originally after taking NAC for just a few weeks. I was recently diagnosed with an ascending aortic aneurysm, and that issue has dominated most of my concern these days. Plus, the lab that I used for testing has recently closed and moved an hour and a half away so I’m looking for a new lab. My doctors won’t test me since my numbers were never that high. According to my original test my chromium was 2.0 and cobalt 2.4 with normal being under 1.2 & 1.8. After just a few weeks the chromium went down to 1.7 & Cobalt dropped to normal at 1.5. If I test again I will update this post.

Jump to this post

@closer0043 one more thing; I have a Quest Lab in my town. I can order a cobalt serum test and a chromium test from them myself and pay them direct. The cobalt was about $150, and the chromium was around $80. Since you mentioned your doctor won’t order the tests; might be an option.

REPLY
Profile picture for closer0043 @closer0043

I have 2 resurfaced hips that are cobalt & chromium. My levels were about double the normal level which I was told isn’t unusual for 2 metal hips. I started taking NAC every morning, and after acouple of months, both my levels dropped to normal and near normal.

Jump to this post

@closer0043 what is NAC

REPLY
Profile picture for djg1951 @djg1951

@djg1951 what test is done to determine these levels of chromium? Can most labs do the test?

REPLY
Profile picture for djg1951 @djg1951

@djg1951 what test is done to determine these levels of chromium? Can most labs do the test?

Jump to this post

@djg1951 Your doctor (either ortho or primary) can order chromium and serum cobalt blood tests. If the local lab where you are doesn't process them, they are sent out to a larger lab. If you are concerned about metallosis from metal on metal implants, it might be wise to ask for one to be done.
Are you having issues from an implanted joint?

REPLY
Profile picture for Sue, Volunteer Mentor @sueinmn

@djg1951 Your doctor (either ortho or primary) can order chromium and serum cobalt blood tests. If the local lab where you are doesn't process them, they are sent out to a larger lab. If you are concerned about metallosis from metal on metal implants, it might be wise to ask for one to be done.
Are you having issues from an implanted joint?

Jump to this post

If a person is found to have a sensitivity to the metal they used what is their alternatives? I had allergies to certain erring metals when I was a kid. I never thought to share this with my surgeon.

REPLY
Profile picture for djg1951 @djg1951

If a person is found to have a sensitivity to the metal they used what is their alternatives? I had allergies to certain erring metals when I was a kid. I never thought to share this with my surgeon.

Jump to this post

@djg1951 There is a difference between metallossis, which is excessive levels of metal in the body, and metal sensitivity, where the body reacts to specific metals.

I would think your allergy as a child was to nickel, which is pretty common. Most implants and their components are made of titanium. chromium, cobalt, and ceramic, which cause far fewer allergic reactions. The few components which contain stainless steel are typically made of grades containing very little nickel specifically to minimize allergic reactions.

If you want to take a "deeper dive" into understanding this topic, I recommend this recent article:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9674446/
Do you think that you are having an allergic reaction to your implant?

If you are concerned about sensitivity/allergy you will need to discuss it with your orthopedic surgeon to find out whether you are reacting to a metal, and what options you have.

REPLY
Please sign in or register to post a reply.