Hereditary depression has a cure?

Posted by lauracaballero @lauracaballero, Aug 15, 2021

Hello, i’ve been on SSRI’s for almost two years now and it doesn’t seem to have a long term effect, first i started with vortioxetine and at about 10 months it stopped working, so my dr changed me to desvanlefaxine, for certain reasons i had to use them for a longer period that was supposed to, but when he finally said that i should start lowering the dose and stop it in about three weeks the symptoms began again, basically they only seem to work while i’m on the medication. While talking with the dr the last session he said that it could be an hereditary factor or “part of one’s personality” (i dont quite remember the exact words) which makes me believe that it could not be cured? as in i might need to be on medication my whole life? he also mentioned about environment issues that may deminish it over time if they change, but im not so sure i understood correctly. My question goes about: is it possible to need medication all my life? i honestly don’t want to because i thought it was going to be a 1 year treatment tops

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@sandfred

In my experience Doctors tell you a year to see how you do and also a year later it is easier to break it to you if they think you need to be on it longer or most likely for the rest of your life. Think about it…what state were you in the 1 year before? Probably not a very good state if they are putting you on meds. Hearing & thinking about it being life long is something hard to accept & takes time. Everyone is so different. Just take one day at a time & when you have the energy try different avenues. How many times (likely without meds) have you had depression in your life? Have you had it a couple of times? If so it is likely you will not be able to bounce back this time if you have had it a couple of times. This is just all info from personal experience. I am 65 & had it since teenage years. I would suggest looking into ketamine treatment. It’s a bit odd but they have had some success with it. This is the only thing I have heard of that has given “some” people relief for a good while or for some permanent relief and get off meds. For myself it DID relieve me of the “bad self talk” (continually putting your self down) but sadly did NOT lift or “cure” the depression. I was not one of my doctor’s success stories but just getting rid of the bad self talk was worth it. Best of luck to you. It will be a journey. God never wastes a bad experience if you let him use it.

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@sandfred You raise an interesting point, in the treatment of and living with depression. Anytime we make a change, we have to be patient to see if it will work for us. Our depression does not come on suddenly, it usually creeps up, although we may not notice it until it becomes a mountain in our lives. So, to whittle that mountain down, it takes time. There are many types of treatment that can be tried, and if one is not working, that adds more time to the mountain coming down.

Each one of us is different. The combination that has worked for me is a low dose citalopram [SSRI] and talk therapy combination. Exercise, stress relieving pastimes [crafting, reading, writing] have played a big part.

Your last sentence is a profound statement. Thank you!
Ginger

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I agree with what you saidGinger. It is worth trying different things because we are different. if it is not working and yes it does take time! AND yes it is a mountain some days! I think I have tried it all! Sharing what works is great since we never know what may work for someone else. Thanks for your reply.

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@sandfred

Could you tell me what the SNP/link it is on the DNA?

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Not sure what “SNP/link is…can you give more detail. This report is kinda old…back in 2015? I think

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Oh ok not well versed in the DNA. Thanks anyways.

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@gingerw

@sandfred You raise an interesting point, in the treatment of and living with depression. Anytime we make a change, we have to be patient to see if it will work for us. Our depression does not come on suddenly, it usually creeps up, although we may not notice it until it becomes a mountain in our lives. So, to whittle that mountain down, it takes time. There are many types of treatment that can be tried, and if one is not working, that adds more time to the mountain coming down.

Each one of us is different. The combination that has worked for me is a low dose citalopram [SSRI] and talk therapy combination. Exercise, stress relieving pastimes [crafting, reading, writing] have played a big part.

Your last sentence is a profound statement. Thank you!
Ginger

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When I 1st started researching my report, because Dr’s always low me off. I don’t “respond” the same as everyone else, they must assume I’m just trying to get drugs. My history started with a motorcycle wreck.. I was a teenager, I thought all was well until I got older.. in fact, the Dr that had my DNA test done was just like everyone else…she prescribed something I told her didn’t work well for me, so she did this test done (to prove her point). I’m glad I have it. But she never went over it with me, she left. So EVERYTHING I know, (which isn’t a lot) I did my own research. I think a MAJOR factor is metal from a hip replacement. I had for 16 years. Metal ions build & I have NO idea they’ll stay in my system. Just for the record…that Dr left too. The orthopedic surgeon who did my revision!
Like 5 months later. 🤷‍♀️

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