HCM Fatigue and Poor Sleep - What Can I Do?

Same thing happened to me sleeping only 4 hours after starting 5 mg camzyos.
I am taking a shower in the afternoon that helps me relax then I take a nap in the afternoon for about 2 more hours which helps a lot.
My first echocardiogram showed the pressure in my heart when down from 195 mm Hg to only 12 mm Hg in only 3 weeks and a half. Since then that I saw that big progress, I am able to sleep now 6 to 6.5 hours per day and I still take a 1 hour nap in the afternoons. This is not fixing the problem but is helping.
In other words, trying to relax and not being worried about my severe HCM since camzyos is working really well is allowing me to sleep better now (not as much as I want but at least I can sleep 6 hours a day which is not too bad).
I hope this helps you. Try to relax and remain positive.

I have been on 5mg of Camzyos for 6 days. I was always fatigued before and since taking Camzyos, I have not been able to sleep more than 3-4 hours per night. I wanted more energy, but I was not expecting this side effect. As a senior, I was always able to fall asleep quickly, though I would often awake for several hours during the night. Now, I am unable to fall asleep and when I am finally able to in the wee hours, I am only able to sleep for a few hours. Has anyone else experienced this as a side effect of taking Camzyos?

I'm so sorry you don't feel well and are always tired. I have no answers, just hope you improve and please call a nurse at your cardiologist office to inquire about your symptoms.

My last meal no later than 5:00 pm helps me to sleep better. If I eat any amount of food after 5:00 pm I cannot sleep well for the rest of the night.

Yes I do, I am on Camzyos 5mg (for 28 days now) and also Metoprolol succinate ER 50 mg (evenings) also Metoprolol 100 mg (early morning), rosuvastatin 20 mg (crestor).

My first echo: LVTO pressure when down from 196 mm Hg (with no camzyos at all) to now only 10 mm Hg in only 3 and a half weeks with camzyos. My septum diameter has not go down yet but I will still be on 5 mg one more month then another echocardiogram will have the doctor decide if camzyos dosage needs to be increased or not.

As soon as I saw the echo results with significant improvement on the pressure gradient, I was able to sleep for the first time in months 7 hours!!! I am not going to get worried or stressed anymore for that make my sleep apnea worst and also does not allow me to sleep enough every nigh so by relaxing and keeping positive attitude and mind I must be fine. I will keep taking 2 mile walk every day.
I hope you feel better soon.

are you on anything except Camzyos? I also have mitral valve stenosis and regurgitation.
On Metroprol succinate ER.
Trouble sleeping and tired.

I have HOCOM, murmur and leaky valve. Taking camzyos now which for some reason keeps me away till midnight.
I take a shower in the afternoons then I take a nap (the shower allows me to sleep in the afternoon and relaxes me). I put soft music in the background at low volume that helps me relax and fall sleep. I hope this helps you.