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Have stage 4 NSCLC being treated with Targeted Therapy, Any one else?
Would love to hear from others who may be having this treatment or have had it in the past. Here's my story:
Long time smoker, had a cough for a few months and then started getting short of breath. Chest Xray showed Pnuemonia, recommended CT Scan of the Chest, CT showed left lower lobe mass, Right hylar mass and swollen lymph nodes, right upper lobe mass. Recommended CT PET Skull Bass to Knees, PET CT showed metabolic activity in the lung areas and mediastinum. No other organ Involvement. Recommended Biopsy. Pulmonologist biopsied all suspected area's of the lung and ordered a Circulogene Blood test to look for genetic variants in tumor cells to make Targeted Therapy possible. Biopsy showed Left lobe was cancer. Lymph modes were Positive for Cancer cells. Right lobe was Negative. Mayo oncologists ordered brain MRI prior to consultation and Brain Mri showed 6 small metastatic lesions in my brain. Being treated with Lazertinib and amivantamab for the EFGR variant I have. Please share if you have experience with this. Thanks
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I have NSCLC with Mets to brain, diagnosed June 2004, non smoker, at the age of 79! Had four rounds of chemo-Cintplatin & Altima (not sure of the spelling one radiation treatment to the brain lesions, targeted with EFGR and have been on Tagrisso since July 10, 2024. My scans have had no evidence of disease times one & half years. I’m 81 now and have my limitations and the Tagrisso has side effects, but I push through and praise God!
I pray that you will have good results!
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11 Reactionshi @kenber45 - I hope your treatments are going well without difficult side effects. if you enter your targeted therapy medications in the search bar, you can find other posts where they have been discussed here previously. you also might want to search using the brand names. amivantamab is Rybrevant and lazertinib is Lazcluze.
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2 ReactionsI have had 3 weekly Subcutaneous injections of the Rybrevant and been on the Daily Lazcluze for 1 week. Prior to starting the Rybevant I was very short of breath and coughing allot. Literally after the first injection those symptoms subsided and have not returned. The only side effect Ive had has been some minor rash issues around my eyebrows and forehead. They gave me a plethora of soaps and moisturizers to use prophalactivly which I have done. Both my Mayo and local Oncologists felt the benefit of adding Chemo drugs to the Targeted Therapy drugs would not be worth the quality of life issues associated with that combo. I'll get a follow up scan in a month. Im very confident my tumors will be much smaller or gone as the dramatic relief of my pre treatment symptoms indicates it's working well. I feel so good! If this is as bad as it gets I am most blessed! Thanks everyone! Praying for you all.
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8 Reactions@almarodel
Same for you Alma! Love your dress and you out on th sand!