Has anyone changed from Anastrozole to Exemestane?

Posted by rozv @rozv, Jan 7, 2024

I had DCIS 16 yrs ago and developed memory/cognitive issues along w hair loss, joint pain,etc with Tamoxifen so had to discontinue it after 2 years. There were no other AI's back then so that was the end of my treatment . I was diagnosed with a new DCIS in the opposite breast in Feb 2023.. I had surgery, radiation and began Anastrozole in May. The joint pain and insomnia became severe within 2 months with an average of 3 hrs of sleep a nite/napping during the day, heating pads on my knees and back, etc which impacted my life style and marriage. Then I started to experience brain fog/memory issues so discontinued the Anastrozole with a month long break. The joint pain and insomnia resolved, and the memory issues have improved but are still an issue.
I just started on Exemestane 2 days ago and am wondering if anyone else is taking it and what their experience has been?. Thank you for your input and best wishes on your journey.

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charlesgreenberg | @charlesgreenberg | 3 days ago

In reply to @lucylocket "@lesliek808 Has anyone who takes Exemestane have issues with itching ? I also have more joint..." + (show)

@lucylocket
Yes, here. Not bad. Very minimal joint discomfort, much less than before switching from anastrozole to examestane

mistymar | @mistymar | 3 days ago

In reply to @lucylocket "@lesliek808 Has anyone who takes Exemestane have issues with itching ? I also have more joint..." + (show)

@lucylocket I didn’t have that problem with exemestane but only been on the letrazole about 5 weeks and this one is causing it for me. I itch like crazy and have started to have muscle cramps again (haven’t had that problem since I finished the chemo).