Has anyone been on Flomax that had an impact on PMR like symptoms?

Posted by christopherc @christopherc, Feb 3 9:11am

I am a 70 year old male that has had PMR for over 5 years. I recently started taking the generic version of Flomax at the recommendation of my doctor to reduce nighttime awakenings to urinate.

About three days after I started taking it I had what I thought was a very severe flareup of PMR. My entire body was very stiff and sore, much more severe than my normal morning PMR symptoms. I researched the side effects of Flomax and didn’t see much relating to my experience. But 13 days in on the Flomax, my symptoms got so severe I could barely get out of bed or walk. I researched it again and found on a different AI system that there were side effects mimicking PMR. So on the 14th day I stopped taking it and woke up the very next day feeling quite a bit better. It apparently takes 2 to 3 days for the Flomax drug to be washed out of your system. So I’m hoping the improvement continues over the next few days.

I’d be interested in whether anybody taking this medication experienced worsening or reduced PMR symptoms.

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

@christopherc, My PMR has been in remission for over six years now for the second time and I'm on the generic Tamsulosin and have never had PMR flares during the the times my PMR was active but that might just be me. I've been on the medication for 20 plus years but the first five or so I always took it in the morning until one day refilling my RX I was talking to my pharmacist and he mentioned it should be taken at night and I've been taking it in the evenings since then. You might find it helpful to chat with your pharmacist. They seem to know a lot more than the average doctor when it comes to meds and side effects.

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@christopherc, My PMR has been in remission for over six years now for the second time and I'm on the generic Tamsulosin and have never had PMR flares during the the times my PMR was active but that might just be me. I've been on the medication for 20 plus years but the first five or so I always took it in the morning until one day refilling my RX I was talking to my pharmacist and he mentioned it should be taken at night and I've been taking it in the evenings since then. You might find it helpful to chat with your pharmacist. They seem to know a lot more than the average doctor when it comes to meds and side effects.

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@johnbishop
Does Tamsulosin have another name since you’re using a generic? Is this a pill or injection.
Thanks for any help

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That is the name of the genetic Flowmax.

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I’ve been on Flomax and had PMR for about a year. I couldn’t say whether the Flomax impacted the PMR symptoms.

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I haven’t personally taken Flomax, but I’ve seen reports and patient discussions where some people with Polymyalgia Rheumatica or similar inflammatory conditions experienced increased whole-body stiffness, muscle aches, and fatigue shortly after starting it, and while it’s not a widely recognized or common side effect, the timing you described symptoms beginning within a few days, worsening over nearly two weeks, and then noticeably improving within a day of stopping does fit a pattern consistent with a drug-related reaction that can mimic or aggravate PMR-like symptoms, so your experience is plausible and definitely worth raising with your doctor when considering alternatives.

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