Gastroparesis with severe symptoms!

@pdilly @1950 @fourof5zs ... When the local GI doc told me about that drug (Domperidone) that was not FDA approved, I first called a friend who was a radiologist in Sweden.. she said, "don't take that"... so I asked my Primary Care Physician to refer me to Mayo MN... That was a life changing day in my life.. 6 years ago and now doing pretty good even though I am 84..
"Domperidone has been banned in the United States for years because of fatal cardiac arrhythmias among cancer patients who had been prescribed the drug to prevent nausea and vomiting. ... "Unfortunately the different uses of the medication have been tied into the one outcome - fatal cardiac arrhythmia." Nov 11, 2014..
https://www.mayoclinic.org/drugs-supplements/domperidone-oral-route/side-effects/drg-20063481?p=1#:~:text=Domperidone%20is%20a%20medicine%20that,immediate%20supervision%20of%20your%20doctor.

What is domperidone?

Thank you for the article @ken82. My gastroenterologist thoroughly researched domperidone before putting me on it. He also had me make an appointment with a cardiologist to make sure he approved as well before giving me the prescription. (I don’t have any heart issues.)

Here is the statement from the FDA website about why they issued a warning about domperidone in 2004 — “FDA took this action because of the concern about the potential serious health risks associated with the use of domperidone by lactating women to enhance breast milk production.” That’s definitely not an issue for me as I approach age 70 — lol.

Since it has helped me so much with stomach emptying with no side effects, I’m very comfortable taking it. It’s also comforting to know that it’s available throughout the rest of the world — appears that only the USA has not approved it. In some countries it requires a prescription but in most countries it’s over the counter.

What is the source of the 2 quotations you shared. They weren’t included in the Mayo Clinic link so I just wanted to read more about those statements made November 11, 2014. Thanks!

Hello,
I feel for you. I'm going through the same thing for years I have been hospitalized, multiple surgeries on my stomach and colon with no answers.
I was diagnosed 2 weeks ago.
I do exactly the same things as you. I vomit after every meal and my food just sits on my stomach and ferments, then I get extremely nauseas.
I had a gastric emptying study by they couldn't complete it bc I threw up the oatmeal.
I have had 15 colonoscopies, 8 endoscopies all in the last 2 years.
I'm am being sent to the Mayo clinic to see what they can do.
Please reply back to me..
Thanks

Domperidone has too many side effects, warnings and interactions with other drugs for me to be comfortable taking it - arrhythmias specifically.

@pdilly @1950 @fourof5zs ... When the local GI doc told me about that drug (Domperidone) that was not FDA approved, I first called a friend who was a radiologist in Sweden.. she said, "don't take that"... so I asked my Primary Care Physician to refer me to Mayo MN... That was a life changing day in my life.. 6 years ago and now doing pretty good even though I am 84..
"Domperidone has been banned in the United States for years because of fatal cardiac arrhythmias among cancer patients who had been prescribed the drug to prevent nausea and vomiting. ... "Unfortunately the different uses of the medication have been tied into the one outcome - fatal cardiac arrhythmia." Nov 11, 2014..
https://www.mayoclinic.org/drugs-supplements/domperidone-oral-route/side-effects/drg-20063481?p=1#:~:text=Domperidone%20is%20a%20medicine%20that,immediate%20supervision%20of%20your%20doctor.

@pdilly Domperidone is available in Canada in prescription. I have had no ill effects or interactions with it. I used to take it at bed time any night I had had a heavy meal but for the past few years I have stopped eating from 9:00 p.m. through the night so I have not needed it.

@pdilly @annieoh ,

I tried domperidone in 2013 and I had several side effects.. I don't remember what they were now and not sure where the paper is I wrote them on. I got the prescription from a doctor at the Mayo in Jacksonville. I had it filled at a local compounding pharmacy. My insurance did not pay for it and I don't remember the cost. Worth checking at local compounding pharmacy for first try.. I got two week's worth. I think I made it a week and a half before I said I'd rather put up with the disease than the medication. It works for many people though.

I am going to mayo in Jacksonville next month to see Dr. lacy he is supposed to be one of the best GI's in the country. I was just researching domperidone and it says it is no longer available in the US. That's crazy, if it works that well then why can't they make it in the US and how would we get it?