Thanks for your quick reply.
I had stage II bladder cancer. Cystoscopy surgery to remove tumor, then Cisplatin treatment. CT scan still showed something, so another cystoscopy surgery to get biopsy and determine cancer free. Am looking for less invasive means of routine testing to detect possible recurrence. How often should this test be done?
I had the test about 2 months ago. Simple blood draw. I have difficult to diagnose symptoms and read about it in AARP. Since then, I have seen it other places. I took it based on the cleveland clinic article. I suggest that you read about it on the Grail website. What I like about it is that in a study they found it had some accuracy for cancers that normally do not have any routine screening test available such as ovarian cancer and pancreatic cancer. Plus I had a positive on the cologard test and a follow up colonoscopy. But that the colonoscopy did not cover small bowel cancer. What I do not like about it is that it was $945 out of pocket. I do believe it is the screening of the future. They just need to make it covered by medicare and other health plans.
Are there any statistic on the possibility of false negative results. I tested positive with a urine FISH test. Trying to determine if it is a false positive. Still looking for the best, accurate non-invasive test to avoid unnecessary surgery to do biopsy.
I had the test about 2 months ago. Simple blood draw. I have difficult to diagnose symptoms and read about it in AARP. Since then, I have seen it other places. I took it based on the cleveland clinic article. I suggest that you read about it on the Grail website. What I like about it is that in a study they found it had some accuracy for cancers that normally do not have any routine screening test available such as ovarian cancer and pancreatic cancer. Plus I had a positive on the cologard test and a follow up colonoscopy. But that the colonoscopy did not cover small bowel cancer. What I do not like about it is that it was $945 out of pocket. I do believe it is the screening of the future. They just need to make it covered by medicare and other health plans.
Hi Hopeful 2:
Did you deal with Grail Therapeutics directly or through your doc? I have not had cancer but do have family history—would really like to know if I am dealing with something serious as soon as possible.
Hi Hopeful 2:
Did you deal with Grail Therapeutics directly or through your doc? I have not had cancer but do have family history—would really like to know if I am dealing with something serious as soon as possible.
The test has a very low false negative, so if it comes back negative you are in great shape. If it comes back positive, there is a 40% chance it is wrong and further testing must be done to prove a positive.
The test has a very low false negative, so if it comes back negative you are in great shape. If it comes back positive, there is a 40% chance it is wrong and further testing must be done to prove a positive.
Hi. I understand. However it’s the only indicator of any kind for certain kinds of cancer. I was curious about the process you followed. Did you access the test through Mayo or did you contact Grail directly? Thanks.
Hi. I understand. However it’s the only indicator of any kind for certain kinds of cancer. I was curious about the process you followed. Did you access the test through Mayo or did you contact Grail directly? Thanks.
Yes, I have had stage II bladder cancer, successfully treated and was using it to make sure a custom test by Signatera Was accurately testing me negative. I told my doctor and he ordered the blood test using the Galleri web site. No connection with Mayo.
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Hello @donsunlover. You ask a great question and one that I hope this article can provide some more answers to.
- Early Cancer Detection Test Studied at Mayo Clinic: https://newsnetwork.mayoclinic.org/discussion/groundbreaking-early-cancer-detection-test-studied-at-mayo-clinic-introduced-nationally/
Where did you learn about this test? Is this of personal interest to you?
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2 ReactionsThanks for your quick reply.
I had stage II bladder cancer. Cystoscopy surgery to remove tumor, then Cisplatin treatment. CT scan still showed something, so another cystoscopy surgery to get biopsy and determine cancer free. Am looking for less invasive means of routine testing to detect possible recurrence. How often should this test be done?
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Like -
Helpful -
Hug
1 ReactionI had the test about 2 months ago. Simple blood draw. I have difficult to diagnose symptoms and read about it in AARP. Since then, I have seen it other places. I took it based on the cleveland clinic article. I suggest that you read about it on the Grail website. What I like about it is that in a study they found it had some accuracy for cancers that normally do not have any routine screening test available such as ovarian cancer and pancreatic cancer. Plus I had a positive on the cologard test and a follow up colonoscopy. But that the colonoscopy did not cover small bowel cancer. What I do not like about it is that it was $945 out of pocket. I do believe it is the screening of the future. They just need to make it covered by medicare and other health plans.
Are there any statistic on the possibility of false negative results. I tested positive with a urine FISH test. Trying to determine if it is a false positive. Still looking for the best, accurate non-invasive test to avoid unnecessary surgery to do biopsy.
Hi Hopeful 2:
Did you deal with Grail Therapeutics directly or through your doc? I have not had cancer but do have family history—would really like to know if I am dealing with something serious as soon as possible.
The test has a very low false negative, so if it comes back negative you are in great shape. If it comes back positive, there is a 40% chance it is wrong and further testing must be done to prove a positive.
Hi. I understand. However it’s the only indicator of any kind for certain kinds of cancer. I was curious about the process you followed. Did you access the test through Mayo or did you contact Grail directly? Thanks.
Yes, I have had stage II bladder cancer, successfully treated and was using it to make sure a custom test by Signatera Was accurately testing me negative. I told my doctor and he ordered the blood test using the Galleri web site. No connection with Mayo.
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1 ReactionI got false negatives from both Galleri and Signatera 2 weeks before MRI spotted a 2cm malignant tumor recurrence on my pancreas. Not impressed…
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3 ReactionsThanks for the info on false negatives. I am taking these tests to check for recurrence of bladder cancer. Mri shows cloudy, possibly scar tissue from previous operations.
Apparently these tests are changing and so are numbers of false positives and negatives. Don't know what to think????
https://www.genomicinterpretation.org/grail-galleri-testing-proving-to-have-high-false-positive-rates/
https://www.genomicinterpretation.org/response-of-lab-transparency-survey-june-20-2023/
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