Connect
Fatigue while on Abiraterone + Prednisone + Lupron Depot
My husband has been on abiraterone, prednisone (both Dailey and Lupron Depot (every 3 months) or 1.5 years. He takes a nap in the morning about an hour after he gets up; a nap in mid afternoon and falls asleep watching the news right befor dinner.
Is this normal?
Like
Helpful
HugInterested in more discussions like this? Go to the Prostate Cancer Support Group.
Connect
I took Lupron + Abiraterone + prednisone for 2.5 years starting at age 76.5, & didn't notice any fatigue. When I went off of it all two years ago, I didn't notice any difference either.
@readandlearn
I didn’t have any fatigue either, but I’ve worked with people that have had serious severe from it. 5 mg of prednisone doesn’t restore enough cortisol for everybody and for those it doesn’t supply enough cortisol fatigue is inevitable.
I was on Lupron, Zytiga, and 5mg prednisone. Severe fatigue. Upped prednisone to 10mg. Helped a bit with fatigue. Then started cutting back to begin a "holiday." Getting off the prednisone was horrible. Reduced pred from 10 to 5. That triggered the most fatigue I'd ever experienced. Had to find a doctor that would Rx pred in 2.5mg doses. Took 6 weeks to get off the pred reducing a little at a time. I'm probably an outlyer with this kind of reaction. Just beware of getting off pred.