Exciting Phase 2 Results from the ARINA-1 Trial!!

Posted by becleartoday @becleartoday, May 1 10:17am

Hi Everyone,

CLINICAL TRIAL UPDATE✨✨
GREAT NEWS ABOUT ARINA-1 nebulizing therapy clinical trial (NOT AN ANTIBIOTIC)!!

Were you in the trial? If so, thank you!!! ✨✨

"These results highlight the important role that ARINA-1 could play in the treatment of non-CF bronchiectasis and are extremely encouraging for patients," said Charles Daley, MD, Professor and Chief, Division of Mycobacterial & Respiratory Infections at National Jewish Health in Denver, Colorado.

"ARINA-1’s novel mechanism improved quality of life and also improved mucus biomarkers in people with bronchiectasis," said Carolyn Durham, PhD, Chief Scientific Officer of Renovion.

"The quality of life data confirms that improving mucus biomarkers, such as viscosity and NE (neutrophil elastase) can reduce symptoms and also improve patient outcomes in this underserved patient population.

These data provide a strong rationale for the continued development of ARINA-1 for NCFBE patients, as well as other populations that suffer from mucus symptoms. We look forward to further analyzing the data and discussing next steps with regulatory authorities."
https://tinyurl.com/yskwez7n
Renovion will discuss study results at the American Thoracic Society Meeting (May 17-22) and present findings at the World Bronchiectasis Conference (July 4-6) in Dundee, Scotland.
Excerpts from BusinessWire April 30th

Warm regards,
Linda Esposito

PS- What's better than sharing good news?

Interested in more discussions like this? Go to the MAC & Bronchiectasis Support Group.

irenea8 | @irenea8 | May 2 7:16am

when do they project availability?

becleartoday | @becleartoday | May 2 7:23am

They will be reporting on it and hoping to do a much larger study. In the previous study, there were only 50 participants. Before they can present it to the FDA they need to do a phase 3 clinical trial. It’ll be available at more sites and more of us will be able to participate. I hope It’ll be offered in New York!

raney | @raney | May 3 10:42pm

In reply to @becleartoday "They will be reporting on it and hoping to do a much larger study. In the..." + (show)

that is good news. I hope it will be offered in North Carolina.

becleartoday | @becleartoday | May 4 5:14am

The company is from North Carolina so I would imagine so!

msk | @msk | May 4 5:43am

How can we get information on the new clinical trials. Would like to try to get in. Thanks

becleartoday | @becleartoday | May 4 5:48am

When they begin, I will submit to Mayo’s IRB for them to approve posting the trial. I think we’re all excited about this one because it’s not yet another antibiotic!

ncalvan | @ncalvan | May 4 7:05am

Please let us know if Mayo will be recruiting for the study. I’m in TN with no NTM or BE providers so I video with Mayo dr. I’ll go up there for a trial if they will take me. Thanks

becleartoday | @becleartoday | May 4 7:19am

Will do! Are you in the Tennessee support group? NTM info and research has over 40 support groups. I know the group leader for Tennessee. She’s very well informed.

scoop | @scoop | May 4 11:59am

In reply to @becleartoday "Will do! Are you in the Tennessee support group? NTM info and research has over 40..." + (show)

Any idea on timeframe for the next steps? Sometimes these things seem to take so long!

becleartoday | @becleartoday | May 4 4:33pm

It will be a couple of years. They still have to do a phase 3, and then get FDA approval.

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