Estrogen replacement therapy helps maintain gut mucous membranes

Posted by virginia44 @virginia44, Sep 21, 2019

I recently stumbled upon a research article on the effects of estrogen on the GI tract. Not only does it help to maintain the mucosal barrier lining the tract, longer exposure to estrogen may decrease the risk of gastric cancer. I started thinking about when I went off of estrogen replacement therapy a few years ago (2016) and by looking back at prescription refill dates realized that is when I began to have serious gut problems that required constant medication. I am wondering if anyone else has had experience going on and/or off of estrogen medications, and if so, can you link that event to GI problems.

I am planning to have this discussion with my doctor, but am curious about experiences others may have with this particular issue.

Great! Thanks so much!


If you plan to discuss this with your doctor, you may want to bring a reference for the published research paper. Here is the paper I brought: "Sex hormones in the modulation of irritable bowel syndrome". World J. Gastroenterol. 2014 Mar; 20(10) 2433-2448. There are a couple other but this one is very detailed.
I hope this is helpful.

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Thank you!!

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