Endometrial Cancer Stage IIIC1

Posted by mtstack @mtstack, Sep 6 10:17pm

Spotting in late April.
Referred to gynecologist after abnormal pap showing atypical glandular cells in June
Ultrasound showed endometrial lining thickened to 19.55mm
Collposcopy, scrape of cervix, and endometrial biopsy resulted in endometrial adenocarcinoma FIGO grade 3
Gynecologic consult Aug 4
Complete hysterectomy bilateral salpingo oopherectomy Aug 8
Pathology report: tumor in uterus, 97% invasion of myometrial lining, cancer cells in right sentinel pelvic lymphnode Stage IIIC1
Consult Sep 2: oncologist recommended platinum systemic therapy of six cycles of carboplatin and paclitaxel. Oncologist doesn’t recommend EBRT even though tumor board recommended a referral.

Anyone familiar with this stage and chemo treatment who might be able to share information on side effects. The more I read about chemo, the more I’m afraid to weaken my immune system. Seems like recurrence is likely and wondering about no further treatment?

Interested in more discussions like this? Go to the Gynecologic Cancers Support Group.

Profile picture for aardvark2118 @aardvark2118

I had similar diagnosis to yours. Had chemo and was well prepared by my oncology team and had little issues thankfully. I worked all the way through chemo and 25 EBRT and three brachytherapy. Worst side effect was fatigue. Had chemo on Thursday and worked Friday. Gave me the weekend to rest up. Did have strong cravings for Taco Bell taco two days after chemo each time. Maybe not the healthiest but sure tasted good. Take care

Jump to this post

Ha! - re Taco Bell.
I knew I was “coming back” from chemo fog when I craved potato chips!

REPLY
Profile picture for jeanknoll986 @jeanknoll986

Hi. I was diagnosed in late Jan with very similar case to yours. I had full hysterectomy surgery, with removal of ovaries, fallopian tube, and a portion of my cervix. I had about a month th of recovery, then started chemo. I had 6 cycles of carbo/paclaxital one treatment every 21 days. I was okay until 3rd cycle. I noted the yucky days lasted longer, and I found it difficult to eat. Yogurt and Ensure we're helpful. I had 3 blood transfusions after cycle 3 as my blood was low and I was weak. However, my oncologist was able to reduce the harsher drug as CT scan showed good progress. After chemo, I had about another month of recovery time, then had a PET scan. It showed no more cancer, but my radiologist suggested 25 external radiation treatments and 2 Bracchy treatments after that as preventative for recurrence. I begin those next week. Aside from losing all my hair and having some lingering neuropathy in hands and feet, I feel very good these days. I had a lot of support, I stayed positive, and I trusted my medical team. I am in western Canada, and in spite of what many believe about our socialized medicine, I had the best experience, and did not cost me a penny. Good luck with your journey. You will make the decisions that are best gor you, and it is amazing what our bodies can do!

Jump to this post

So relieved your oncologist was able to adjust your medication. I am a bit worried about becoming more anemic, and hadn't thought about needing blood transfusions. I also feel good on a while for plant based diet but worth about maintaining my weight of I lose my appetite which sounds fairly common.
Thank for for sharing your experience with me. I hope your next treatments go well.

REPLY
Profile picture for Helen, Volunteer Mentor @naturegirl5

@mtstack As ;you weight you options I hope you will come back here to run through your ideas and ask questions. This is a group with a lot of experience to support you.

Jump to this post

I find this group invaluable.
I am so conflicted and relieved to hear I'm not the only one who second guesses treatment options.

REPLY
Profile picture for bocabird @bocabird

Are you on East Coast? Near Florida? I went to Moffett for second opinion and they had a different protocol for chemo and brachytherapy.

Jump to this post

Near to Boston.
I think every opinion will recommend chemo and/or radiation. I was hoping to find someone who had chosen a more holistic approach with their doctor's support.

REPLY
Profile picture for ffr @ffr

I had the carbo/taxol chemo and managed better than expected. I was fatigued and had a diminished appetite the first days after each infusion. Smoothies and soup got me through. Then I would get crazy cravings and I knew that my appetite was back. Sadly, I was deemed to be chemo resistant as I had recurrence to the lymph nodes prior to my final treatment. Then I had external radiation followed by two brachytherapy treatments. Because of my high grade cancer the oncologist threw everything at me after surgery. This was the recommendation of the tumor board as well as the second & third opinions that I sought out. This was before biomarkers became part of treatment decisions.
I hope this helps.

Jump to this post

I'm so sorry to hear that you had recurrence prior to your last cycle. I hope that external radiation and brachytherapy were helpful.

REPLY

The recurrence threw me for a loop and so I am deemed “chemo resistant.” But I just celebrated three years since my final radiation treatment and I would like to think that it has helped, along with the surgeries.
(I do deal with side effects but so far they are manageable, if not annoying.) Three years is a milestone that I wasn’t sure I would reach. I can only hope that my gift of time will allow me to see a breakthrough treatment for aggressive NSMP (no specific molecular profile) cancers like mine. And for all the rest of my EC sisters.

REPLY
Profile picture for mtstack @mtstack

So relieved your oncologist was able to adjust your medication. I am a bit worried about becoming more anemic, and hadn't thought about needing blood transfusions. I also feel good on a while for plant based diet but worth about maintaining my weight of I lose my appetite which sounds fairly common.
Thank for for sharing your experience with me. I hope your next treatments go well.

Jump to this post

I know..I carried a lot of extra weight, lost 25 lbs, which in my case was not a bad thing. Each woman is so unique that the side effects vary so much among all of us. It's a challenge, trying to balance protein needs with zero appetite. I had anti nausea meds, which I used and never vomited. I wish you all the best. Stay strong!

REPLY
Profile picture for mtstack @mtstack

Near to Boston.
I think every opinion will recommend chemo and/or radiation. I was hoping to find someone who had chosen a more holistic approach with their doctor's support.

Jump to this post

Don't think you will get holistic recommendation- with endometrial diagnosis- I was originally stage 1a serous papillary and they recommended carbo taxol and brachy- Moffett said it was Stage 2a since it was going into the cervix and they recommended sandwich therapy. Eight years later my oncologist has said I just need check ups with my primary gyno. So far so good.
I breezed through the chemo treatments-most importantly I iced my feet and hands during treatments and never got neuropathy. Had gorgeous wigs- went out on dates- everyone wanted to know where I had my hair colored ha ha. Lost all hair and eyebrows lashes but everything grew back. First 4 days of treatment horrible but then back to regular activities zumba etc. and eating. Mind over matter.

REPLY
Profile picture for mtstack @mtstack

Near to Boston.
I think every opinion will recommend chemo and/or radiation. I was hoping to find someone who had chosen a more holistic approach with their doctor's support.

Jump to this post

Hello, @mtstack ,

From Vermont, here, so we're nearly neighbors on the Mayo Connect world-wide scale! I have received primary healthcare from Sojourns Community Health Clinic in Westminster, VT since 2011. I see a naturopath who is also a PT and midwife. When my first post-menopausal spotting happened and I called her, she got on the phone right away and said, "you need a gynecologist to do an endometrial biopsy, and don't wait." I was shocked to hear my hippie, herbal wise naturopath say that. When a cancer diagnosis ultimately came back and I heard the recommendations for hysterectomy, oophorectomy, salpingotomy and sentinel node biopsy, I met with her again to ask what other options I had. I didn't want surgery and didn't want "what might follow it" post-surgery. She was quite clear. There are ways that integrative oncology (a naturopath trained in oncology) can help you manage symptoms and side effects of treatment and can support the effectiveness of standard treatment. It can help you to design and live a quality life and maximize your chances of preventing recurrence, but to get the cancer out of your body, you need to advocate for aggressive treatment to start.

There is also an integrative oncologist in Middlebury, VT who I've seen and appreciated very much. I am imagining you can find the same near you. A consult with one might be very helpful for you to clarify all of your options and how they might work together.

I wish you well!!!!

@gynosaur42

REPLY

I never got nauseous- yes all hair fell out- but came back - same with eyelashes and brows- but I made myself look gorgeous with wigs and makeup. First 4 days not great -laid in bed- no appetite - then I was rearing to go- bug appetite -zumba classes- running around etc. I hardly told anybody what I had- I did not want a pity party.

REPLY
Please sign in or register to post a reply.