Doctors claim oxycodone exacerbates pain but nothing else helps

Posted by Jenny @fairymystry, 5 days ago

Hello. I have reached out to the forum before on behalf of my best friend with chronic pain and I am back again with another query....
My best friend had yet another upper endoscopy today to attempt to find a cause for the constant and intense abdominal pain that she suffers. She has a long history of food allergies, gastroparesis & other gastro issues spanning most of her 49 years but, several years ago she began a cycle of getting pancreatitis repeatedly with 6-12 months in between. The abdominal pain has never gone away & is so intense that she can no longer work, especially since she had a nerve block a couple of years ago that she claims actually made it worse. She now relies heavily on the oxycodone & it doesn't take her pain completely away but she is able to function at least. It is the ONLY thing that seems to work for her and she hates it because of the side effects.
Today after the latest endoscopy, this doctor joined a series of docs that have suggested that the oxycodone she takes to relieve the pain is actually exacerbating the pain and that she should consider getting off of it. The doctor that renews her prescription for it monthly doesn't seem to see that as an issue & my best friend doesn't know what to do because of course she'd love to get away from the oxy but the pain is too intense without it and no one seems to have an alternative for her.
I guess I came here to ask if anyone else has heard that the opioid they take for pain may be making it worse & if there are non-opioid alternative that actually work for this type of pain.

Interested in more discussions like this? Go to the Chronic Pain Support Group.

@tntwo99

There is no difference as they are the same mg. However, hydrocodone is more likely to cause constipation.

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They are not the same. Oxycodone is the stronger of the two and about 1.5 times as potent as hydrocodone. In other words, 30 mg of hydrocodone is equivalent to 20 mg of oxycodone.

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@marialyce

They are not the same. Oxycodone is the stronger of the two and about 1.5 times as potent as hydrocodone. In other words, 30 mg of hydrocodone is equivalent to 20 mg of oxycodone.

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That depends on who is doing the research. Speaking to 10 different PharmD docs, they have all said they are the same.
Both medications are strong painkillers, and they are incredibly effective at managing pain in individuals. In the Placebo Effect study, researchers found that participants experienced equal pain relief 30 and 60 minutes after taking medications and saw similar side effects. But those who took HC experienced constipation more often than participants who had OC.

The study comparing the efficacy of oral analgesics found no significant difference between Hydrocodone and Oxycodone when combined with acetaminophen (APAP) to ease acute musculoskeletal pain. Nearly 60% of participants in both groups reported a significant reduction in discomfort.
To some researchers and healthcare professionals, OC is more potent than HC. In addition, according to the Drug Alcohol and Dependence study, the combination of Oxycodone APAP was 1.5x stronger than the combination of Hydrocodone and APAP in terms of pain treatment.

I have used both and found no difference.

Have to tell you that I love your name. If I had delivered a second daughter, her name would have been Marialiese. My daughter is named Annaliese.

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@mggrubbs

I have chronic back pain also which was also unmanageable. I had the ablation or burning of the nerve to relieve the pain. The first one lasted 16 months of relief. Last year I had a 2nd one & so far it’s been 15 months and I’m just starting to feel the pain. So maybe you should try the ablation. It’s worth a try. I’m very happy with it.

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Thank you for your response. I'm glad you got relief from the pain. I'm required to have 2 additional appointments and 12 shots to see if I can even have the ablation. Ugh

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@dbrdiana

My experience with oxygen has been good for controlling pain in the past. My doctor was only concerned about it being addictive and because of state laws, I had to sign a release and provide ID when picking up the medication. I still have to see him in person for a refill.

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There's a typo in my listing. Oxygen should have been Oxycodin. Sorry

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I hear your frustrations and share your concern.
I take a small amount of hydrocodone (Vicodin) for nerve/arthritis pain/spinal stenosis - I have had two back surgeries and am fused L2-S1 and my neck surgery fused two levels and now the rest of my neck is essentially self fused.
My internist is retiring end of June and I am concerned that I may not find anyone new to prescribe it for me. I have a huge collection of “pain relief” ointments, roll ons, creams, etc. I have gone to PT many times. I was told to not go to a chiropractor (and the last one years back sent me to a neurosurgeon!). I can no longer take aspirin or other NSAIDs because I got gastritis, lost 20#. I am not overweight and am in good shape otherwise. I stretch. I use cold/ice and heat…
Feeling your pain!

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