Do side effects of Hormone therapy get better in time?

Posted by destiny86 @destiny86, Sep 9 12:29pm

Just wanted to hear any experiences whether the side effects of antihormone therapy get better in time? What experiences Do you have? Habe severe depression and antidepressants don't work. But I have to take antihormone meds because I am a high risk Patient. I have already tried letrozole and Tamoxifen. Now on exemestane. I should take abemaciclib alongside with it but cannot take it due to the side effects😞.

Regards

Destiny

Interested in more discussions like this? Go to the Breast Cancer group.

In my experience side effects of all hormonal drugs get better over time. You also have the option of taking an AI on alternate days.

REPLY

What Do you mean with AI on alternate days?

REPLY
@destiny86

What Do you mean with AI on alternate days?

Jump to this post

Most endocrine therapies are effective at a percentage of the normal dose, @windyshores has done some reading on this, meaning you could take them on alternate days giving you less side effects. That being said if it is effective there will be the side effects from the loss of hormones. The hot flashes and night sweats etc. similar to menopause.
I did not have unbearable side effects, but I did require some Zoloft every day in order to hold off the depression, that came with it. I also have had some bone loss due to the long term lack of hormones. I have certainly gotten less limber and strong over the years of endocrine treatment but I don’t have to ask if I have done everything possible to hold the cancer at bay.
Most of the initial side effects passed within a few months, only the menopausal symptom seemed to hang around.
What side effects are you experiencing? May I ask if you are pre or post menopausal?

REPLY

I am pre menopausal. And I think the side effects are from the Lack of hormones. They occur with any med. I have severe depression and antidepressants don't help me.

REPLY
@windyshores

In my experience side effects of all hormonal drugs get better over time. You also have the option of taking an AI on alternate days.

Jump to this post

Alternate days? Could you say more about this? I would like to learn more and read more about this option. I understand that Anastrozole has a half life of 50 hours and may hang out even more for older women. I would be in that category. Going to discuss with oncologist at next appointment. Thank you.

REPLY
Please sign in or register to post a reply.
  Request Appointment