Day 2 on Zoloft

Posted by brosha1234 @brosha1234, Apr 25 12:30pm

I’m on day 2 taking 25 mg of Zoloft I’ve been taking it at 7:45 pm. My first day on it I had horrible diarrhea & headache. I just didn’t feel connected to my brain (really spacey) and I have absolutely no energy I just want to sleep. Do these symptoms get better or anyone experience something similar?

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Hi…Just figured I’d comment on my side effects..(years ago) when beginning Zoloft. I had a lot of nausea in the beginning (no actual vomiting tho) and I do remember feeling an “aloofness” in the beginning too…For instance…what normally would irritate me…such as…my kids arguing/annoying each other & things like that-did NOT seem to have an effect on me anymore. However, I believe my dose began at 50 mg..NOT 25mg.
I hope you feel better soon/or that your body adjusts to it. Take care 🙂

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I started at 1/2 of a 25 mg tab (12.5 mg) which seemed ok for a week, then bumped it up to 1/2 of a half and had the same "don't give a darn feeling," and sooo sleepy I couldn't keep my eyes opened. So I wasn't even at the lowest prescribed dose. Did two days of that then quit! So now, not aloof and sleepy, just still depressed and anxious!

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I was on it for a few years. I had no side-effects from it.

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I could only tolerate and wouldn’t even call it that the medication for 4 doses. The insomnia, irritability, anxiety, panic attacks, acid indigestion, feet & hands sweating yet cold, nausea just to name a few of my symptoms were unbearable. I was hungry but yet couldn’t get myself to eat. Like a recluse locked away in my room in bed for days. I was not having any of those issues listed above before starting Zoloft except anxiety w/was spells of depression. I was basically at my Witt’s end so decided last night not to take my medication. I actually slept the first time throughout the night in 4 days, I’ve been doing little things around the house to try to keep myself busy from watching the clocks. I’m hoping as the days go on I start feeling better and more like myself.

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@kndaustin71

I started at 1/2 of a 25 mg tab (12.5 mg) which seemed ok for a week, then bumped it up to 1/2 of a half and had the same "don't give a darn feeling," and sooo sleepy I couldn't keep my eyes opened. So I wasn't even at the lowest prescribed dose. Did two days of that then quit! So now, not aloof and sleepy, just still depressed and anxious!

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What are you doing now for your depression & anxiety?

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@brosha1234

What are you doing now for your depression & anxiety?

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All of this transpired over the past two weeks....I quit taking the Zoloft, was surprised to see so many negative comments from folks. However, I told the Dr that I had difficulty tolerating SSRI's in the past. Currently, I am only taking Xanax 0.5 mg for the anxiety in the am and 1.5 mg at nite for sleep which is working fine. I contend that I am depressed because I have such high anxiety, not that I have depression that is causing the anxiety.

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@kndaustin71

All of this transpired over the past two weeks....I quit taking the Zoloft, was surprised to see so many negative comments from folks. However, I told the Dr that I had difficulty tolerating SSRI's in the past. Currently, I am only taking Xanax 0.5 mg for the anxiety in the am and 1.5 mg at nite for sleep which is working fine. I contend that I am depressed because I have such high anxiety, not that I have depression that is causing the anxiety.

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I had horrible time years ago with many SSRI’s I went through so many I lost count. They just weren’t doing well with my brains chemistry I just was extremely sensitive & had super crazy side effects. I too have really high anxiety never really dealt with depression except getting depressed with this darn anxiety 😥

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My husband has had such a difficult time with anti-depressants and anti-anxiety meds, we too have lost count of how many have been tried. Most of his Long Covid symptoms have subsided after 13 months but depression and anxiety continue which I believe are worsened by the meds. He is too nervous to stop taking them completely. It is heartbreaking to watch him struggle through the days crying. Doesn't anyone have an answer for this crushing aspect of Long Covid?

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@brosha1234

I had horrible time years ago with many SSRI’s I went through so many I lost count. They just weren’t doing well with my brains chemistry I just was extremely sensitive & had super crazy side effects. I too have really high anxiety never really dealt with depression except getting depressed with this darn anxiety 😥

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Alot of people can't tolerate the SSRI's or the SSNRI's, however there are lots of other medications that can assist with anxiety. I contend that you probably would not be as depressed if you could get the anxiety under control. Perhaps speak to your physician who would discuss the different treatments for anxiety of find one that is willing to do so. To let you suffer needlessly with anxiety when there could be treatment options is unconscionable!

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@brosha1234

I could only tolerate and wouldn’t even call it that the medication for 4 doses. The insomnia, irritability, anxiety, panic attacks, acid indigestion, feet & hands sweating yet cold, nausea just to name a few of my symptoms were unbearable. I was hungry but yet couldn’t get myself to eat. Like a recluse locked away in my room in bed for days. I was not having any of those issues listed above before starting Zoloft except anxiety w/was spells of depression. I was basically at my Witt’s end so decided last night not to take my medication. I actually slept the first time throughout the night in 4 days, I’ve been doing little things around the house to try to keep myself busy from watching the clocks. I’m hoping as the days go on I start feeling better and more like myself.

Jump to this post

I too was prescribed the lowest dose of Zoloft.25 mg. It presented me with terrible side effects. Terrible headaches, restless leg syndrome, diarrhea, clenching jaw so badly cause facial pain, blurry eyes, severe dizziness, felt so weird, serious shaking,
legs & hands. I stayed on it for 8 weeks and my body never adjusted.
I weaned myself off and it going on a full 2 weeks and i still feel anxious, weird, headaches, muscle pain, and grinding teeth & jaw pain.
The absolute worst medication ever. Im thankful I’m off it but
Still feel weird snd unlike myself.

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