Cymbalta

Posted by popolopo @popolopo, Sat, May 11 8:04am

I have tried Cymbalta (Duloxetine) but I can't fall sound asleep with it. I would like to give it a chance but I need to sleep. I take it for pain after my hip replacement.

Hi @popolopo that must be frustrating that you haven't been able to sleep while on Cymbalta.

I wanted to introduce you to fellow Connect members @jeanne51 @elwooodsdad and @petangelkat1as they have experience with Cymbalta and may be able to provide support.

Here is a discussion you may find helpful on Cymbalta withdrawal: https://connect.mayoclinic.org/discussion/what-are-the-symptoms-of-cymbalta-withdrawal/?pg=1#comment-294858

Back to you @popolopo how long have you been on Cymbalta?

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I was on it for 5 days and felt awful so I quit. I tried it again 2 weeks later and lasted one day. It will not let me sleep.

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I had the same issue with Cymbalta. So on a weekend when I didn’t have to work ,I took in the morning and had no problems and now I can sleep again! Plus the Cymbalta has helped so much with depression and pain,

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@boo55

Has anyone experienced sleeplessness from Cymbalta ? I feel some pain relief but I can not sleep. Only taking 30mg a day . I am very sensitive to meds.

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Hello @boo55 — I know it must be frustrating not being able to sleep. I'm tagging our moderator @ethanmcconkey to see if we should combine your post into the following discussion where @popolopo is asking the same question and you can meet @coralbells1 @jeanne51 @elwooodsdad and @petangelkat1 who also have discussed Cymbalta in a post.

> Groups > Chronic Pain > Cymbalta
https://connect.mayoclinic.org/discussion/cymbalta-2/

Has your doctor offered any suggestions to help with the sleep?

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Has anyone experienced sleeplessness from Cymbalta ? I feel some pain relief but I can not sleep. Only taking 30mg a day . I am very sensitive to meds.

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@johnbishop

Hello @boo55 — I know it must be frustrating not being able to sleep. I'm tagging our moderator @ethanmcconkey to see if we should combine your post into the following discussion where @popolopo is asking the same question and you can meet @coralbells1 @jeanne51 @elwooodsdad and @petangelkat1 who also have discussed Cymbalta in a post.

> Groups > Chronic Pain > Cymbalta
https://connect.mayoclinic.org/discussion/cymbalta-2/

Has your doctor offered any suggestions to help with the sleep?

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No,she thinks I gave up too soon. I take Zopiclone to sleep,it works.

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@ethanmcconkey

Hi @popolopo that must be frustrating that you haven't been able to sleep while on Cymbalta.

I wanted to introduce you to fellow Connect members @jeanne51 @elwooodsdad and @petangelkat1as they have experience with Cymbalta and may be able to provide support.

Here is a discussion you may find helpful on Cymbalta withdrawal: https://connect.mayoclinic.org/discussion/what-are-the-symptoms-of-cymbalta-withdrawal/?pg=1#comment-294858

Back to you @popolopo how long have you been on Cymbalta?

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I don’t know if this is appropriate or not but I will mention it and you can delete it if you want. If anyone is on Facebook there is a group called “Cymbalta Hurts Worse.” It is a group that helps people get off Cymbalta and encourages not using it for pain or depression. Use your own discretion but I have been on antidepressants most of my adult life, 30+ years. I have never had such a negative effect from any antidepressant and there are thousands like me. I have had many side effects on Cymbalta and getting off of it. I am still going through withdrawal. It needs to be tapered very slowly. Just a FYI.

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@jeanne51

I don’t know if this is appropriate or not but I will mention it and you can delete it if you want. If anyone is on Facebook there is a group called “Cymbalta Hurts Worse.” It is a group that helps people get off Cymbalta and encourages not using it for pain or depression. Use your own discretion but I have been on antidepressants most of my adult life, 30+ years. I have never had such a negative effect from any antidepressant and there are thousands like me. I have had many side effects on Cymbalta and getting off of it. I am still going through withdrawal. It needs to be tapered very slowly. Just a FYI.

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@jeanne51 I wasn't on it for depression but fibromyalgia and I lasted one dose on it .I started forgetting things I didn't like the way I felt so stopped it .

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@boo55

Has anyone experienced sleeplessness from Cymbalta ? I feel some pain relief but I can not sleep. Only taking 30mg a day . I am very sensitive to meds.

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Hi, @boo55 – how are things going with the sleeplessness you were experiencing from the duloxetine (Cymbalta)?

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@ethanmcconkey

Hi @popolopo that must be frustrating that you haven't been able to sleep while on Cymbalta.

I wanted to introduce you to fellow Connect members @jeanne51 @elwooodsdad and @petangelkat1as they have experience with Cymbalta and may be able to provide support.

Here is a discussion you may find helpful on Cymbalta withdrawal: https://connect.mayoclinic.org/discussion/what-are-the-symptoms-of-cymbalta-withdrawal/?pg=1#comment-294858

Back to you @popolopo how long have you been on Cymbalta?

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I TOOK CYMBALTA FOR 1 DAY. I HAVE HASHIMOTO'S THYROIDITIS. FOR YEARS DUE TO MY MEDICAL CONDITION CALLED "CHRONIC IDIOPATHIC URTICARIA" IT HAD HIVES SO SEVERE I WOUND UP IN THE ER UNTIL FINALLY SENT TO A DR, IN S.C. GAVE ME SOMETHING THAT IS ALSO USED FOR TRANSPLANT PATIENTS, HIVES WERE GONE FOR YEARS UNTUL !!! I TOOK CYMBALTA, HIVES WORSE THAN EVER. WENT TO AN IMMUNOLOGIST GAVE ME INJECTIONS CALLED XOLAIR. HIVES WERE GONE IN 7 MONTHS!! I HOPE NO FLAIR UPS IN THE FUTURE!!

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@boo55

Has anyone experienced sleeplessness from Cymbalta ? I feel some pain relief but I can not sleep. Only taking 30mg a day . I am very sensitive to meds.

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@boo55, Good afternoon. I am grateful for the relief that Cymbalta has given me from the uncontrollable anxiety that was taking over my life. Although my PCP suspected that the neuropathic pain was causing neurobehavioral issues including memory loss, it was confirmed by 4 hours of neurobiological testing. The bottom line….my pain was creating anxiety and the more anxious I became, the greater the pain. It was a huge dilemma for me. I had withdrawn from a volunteer marketing role in the community. I could not play mahjong or other distracting games unless someone at the table helped me remember what was happening next. I had some bouts with suicide. We approached it slowly with Cymbalta because, like you, I am sensitive to meds. Started with 20 mg for a month, then 40mg for the next month and now 60 mg. We decided that morning would be the best time to take this med. That solves the sleep issue and helps me when I need it most…during the daytime. Hope this helps…..have a safe and pain-free day. Chris

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@lioness

@jeanne51 I wasn't on it for depression but fibromyalgia and I lasted one dose on it .I started forgetting things I didn't like the way I felt so stopped it .

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A year ago in April, my PCP tried me on Cymbalta for my fibromyalgia. After 3 days I had diarrhea so badly that I ended up in the ER. It was complicated by having a UTI. Within a few days I lost 8 pounds which for me was not good because I am very thin. After getting well (3 to 4 weeks of being pretty sick) we tried the Cymbalta again. Within a day, I was back to being sick. We put Cymbalta on my growing list of meds I can’t take. Lyrica has been somewhat helpful but I’m not ready to do a commercial for it. My best medicine has been varied but regular exercise.

My fibromyalgia acts differently from that of most fibromyalgia patients I know. It comes and goes in huge waves. I will have a wave of bad days lasting as long 3 or more weeks. Then I will have a reprieve for a while. Right now I am extremely grateful for a “downtime “ of nearly 6 weeks with pain only reaching up to about 3 on a 1 to 10 scale. I’m waiting for this unbelievably good period to end without warning. That is how it usually goes for me. Does anyone else experience high and low waves like this? What do you think causes the come and go?

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Took Cymbalta for months…same issue…no sleep…Dr. that prescribed it …said take in the morning…for pain!!!

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@rubbob1 Hello there…..thanks for sharing your experience with Cymbalta. I would like to know if your statement "for pain" refers to the primary reason for taking the medication. I have just worked through a 3-month process of increasing the dosage from 20mg to 40mg to 60mg. I must say that this medication has done more for me than any other I have tried. My PCP said it was an anti-anxiety medication which works to decrease the anxiety which fosters the increased pain which then leads to more anxiety, which then leads to additional pain, etc. etc. etc. I went through neurobehavioral testing from a clinical psychologist for recent memory loss. Evidently, the anxiety was also responsible for my memory issues as well as neuropathic pain. I was caught up in the anxiety which then caused more pain and eventually depression. So…I take it every morning and my day begins a lot more joyously. In fact, it works so well that instead of anxiety, I now suffer from "who cares" and "so what" demons. Have a day free of suffering and filled with comfort. Chris

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@boo55

Has anyone experienced sleeplessness from Cymbalta ? I feel some pain relief but I can not sleep. Only taking 30mg a day . I am very sensitive to meds.

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May I suggest Trazadone for sleep. It is an Antidepressant taken before bed. I sleep through the night. Have been taking for a long time, for me no side effects that I know of. I took Cymbalta for 1 day. I have Thyroid Autoimmune Disease that has effected me for years, Uticaria I was in remission until I took the pill. Incase anyone has same Autoimmune Disease thought I would add that.

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