Coffee and Multiple Myeloma

Posted by Kali @madkm, Dec 31, 2025

Does anyone have information on whether coffee has a causal relationship with multiple myeloma? I have seen mixed results. I LOVE COFFEE.

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Profile picture for sallik74 @sallik74

@madkm I have SMM too. How long have you been smoldering?

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@sallik74 I was just diagnosed with SMM. From my labs, it looks like all this started 8/23 - 8/24, when my Hg took a real nosedive. It has since come back up, but it's still below normal. Coincidentally (or not), I had a cardiac ablation around that time! Be well.

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Jumping in on this hope you don't mind. I have had SMM high risk 5 years as of this month. Prior to being diagnosed with SMM I had H-Pylori (a severe intestinal infection) for over 4 months and lost 30 pounds during that time. Prior to H-Pylori I drank about 7-8 cups of coffee per day. After the H-Pylori was cured I tried going back to multiple cups of coffee but the SMM diagnosis and treatment , Revlimid and Dexamethasone, allowed me to tolerate a small cup of coffee per day for about 3 years. Now I can consume about 12 ounces of coffee per day but that is it. During and after the H-Pylori I was also diagnosed with diverticulosis so not sure if the H-Pylori, 7+ cups of coffee per day or oncoming SMM high risk was to blame for the diverticulosis. Oncologist and gastro Doctors both said any of the 3 (SMM, coffee, H-Pylori) or any combination thereof could be the culprit.

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I was told to stop drinking coffee because it tends to dry out the system, and I would need to drink more water to keep the kidneys functioning.

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Two years with MM and no problem with my 24 oz. of coffee per day.

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Greetings! Been diagnosed w mm in my "golden" years. Going to start therapy after new blood results. It has been a distressing time, heart problem, mm, death of friend. I am down to one cup of caffeine a day. And go figure, has to be espresso. I have found a comfort in chamomile, lemon ginger and lemon balm teas. No, not the richness of a nice cup of coffee but it is better for my stomach. Interestingly, I can't tolerate tea.

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I have started treatment in a clinical trial that treats smoldering myeloma that is considered high risk.

I am treated with a monoclonal antibody and a bispecific antibody. My taste buds have made it a moot point. I am in the adjustment period but I haven’t enjoyed coffee as much. I do require at least one a day that is espresso strength!!

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Profile picture for mcarre @mcarre

Greetings! Been diagnosed w mm in my "golden" years. Going to start therapy after new blood results. It has been a distressing time, heart problem, mm, death of friend. I am down to one cup of caffeine a day. And go figure, has to be espresso. I have found a comfort in chamomile, lemon ginger and lemon balm teas. No, not the richness of a nice cup of coffee but it is better for my stomach. Interestingly, I can't tolerate tea.

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@mcarre
I'm sorry your stomach issues are keeping you from enjoying your coffee. If it's the acid, there are reduced acid coffee options.

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