Coffee and Multiple Myeloma
Does anyone have information on whether coffee has a causal relationship with multiple myeloma? I have seen mixed results. I LOVE COFFEE.
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@madkm When I placed that into a Google search, it shows there are a few small studies done. Results appear to be inconclusive overall, but you can find results that will support either direction you want to see!
Are you diagnosed with multiple myeloma? For me, I now limit my coffee consumption more because it does tend to upset my digestive tract, and seems to contribute to negative side effects of my medications. Anything to keep my body happy is the way I want to go. How much coffee are you drinking a day?
Ginger
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1 ReactionI have smoldering multiple myeloma. Too much coffee is the answer to how much!
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1 Reaction@madkm Gradually cut back on your coffee. Years ago, I could drink three pots a day, with no stomach upset. Yep, you read correctly! These days it is one or 1.5 cups a day. I often will brew up a decaf pod, or do a cup of hot tea. This time of year I want something warm, and don't want the possible upset stomach. Some people need to have a little something like a cookie or cracker with coffee or tea, to help avoid tummy concerns.
Ginger
@gingerw
Does the research include decaffeinated coffee?? I gave up caffeine in 2023 and switched to decaf. I often wonder if coffee might not be good for my kidneys.
As Ginger wrote, those studies that have been done are small, and their results inconclusive. Among those studies are a few that even show coffee having a PROTECTIVE effect against certain types of cancer.
Another quick note: many of those studies employ so-called "Mendelian randomization" (MR). MR is a complex subject, but essentially involves selecting genetic variants - by nature randomized among the population studied - that correspond to the causal effects of a modifiable exposure (for example, coffee). By studying the change in disease risk those genetic variants produce, the result can imply a stronger link between the risk (or benefit) and the exposure substance. MR can be a powerful tool, since it largely avoids serious issues such as confounding and reverse causation that can arise in traditional randomized control trials. However, that are many aspects of MR that require considerable care and knowledge on the part of the researchers. For those who want to get into the weeds, take a look at https://wellcomeopenresearch.org/articles/4-186
Well, maybe not such a quick note.