How to choose: carboplatin+paclitaxel OR carboplatin+gemzar?

Posted by danuta @danuta, Sep 12 3:45pm

I recently changed to a new Medical Oncologist. Under the care of my first Oncologist, I was on Enfortumae-vedotin (Padcev) treatment for Ureteral cancer, which stopped working after 6 months. My new Oncologist had me take a break from treatment for 2 months.

I’m about to start further treatment with carboplatin + paclitaxel. My previous oncologist had intended to start further treatment with carboplatin gemzar. I’m wondering how these treatments differ and which may be preferable at this stage of my treatment.

(On 9/7/22 I had a pelvis MRI which indicated stable appearance of the right ureteral mass involving the right vaginal wall and increased right pelvic lymphadenopathy)

Thank you

Interested in more discussions like this? Go to the Kidney & Bladder group.

@danuta, that is a very good question that I would discuss with your oncologist. If it were me, I would go to a reputable website and compare the 2 different drug combinations. I would find out
– how they are administered
– what are the most common side effects

For example here are 2 pages from Macmillan Cancer Support:
– GemCarbo chemotherapy https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/gemcarbo
– Paclitaxel and carboplatin https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/paclitaxel-and-carboplatin

I would consider which side effects I would more likely be able to handle. Equipped with that information, I would ask loads of questions like:
– Which treatment has shown to be most effective with ureteral cancer?
– What characteristic of my cancer and personal medical history make one treatment preferable over the other?
– If I were to get XXX side effect, how can it be managed?

Did you ask the new oncologist why they chose carboplatin + paclitaxel rather than GemCarbo? How are you feeling after the chemo break?

REPLY
Please sign in or register to post a reply.
  Request Appointment