Celiac disease and parathyroid issues

Posted by ado79 @ado79, Sep 21 1:25am

I was diagnosed with mgus and sieronegative celiac disease about 10 years ago.
After covid I have discovered my PTH is very low, so I got the hypoparathyroidism diagnosis too.
I wonderin if these these three conditions are related.
Anyone else with the same issues?
Thanks in advance

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No PTH problems, but I've had hypothyroidism for 20 years, celiac for at least 14, and MGUS for 6 years. I also have collagenous colitis and I had Reiter's syndrome in 1989-1990. Once you have an autoimmune disease you tend to collect others. MGUS origin is unknown, but since folks with celiac have a higher incidence of blood cancers there could be some link. A possible correlation between PTH and celiac is the malabsorption of nutrients, including minerals, from a damaged GI tract. Mostly one needs to limit the illnesses as well as you can with diet, meds (synthroid for me), exercise, and stress management.

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@ado79 I had hyperparathyroidism because I had a tumor one of my parathyroid glands. So, I had the opposite problem. My calcium levels were way too high.

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@kayabbott

No PTH problems, but I've had hypothyroidism for 20 years, celiac for at least 14, and MGUS for 6 years. I also have collagenous colitis and I had Reiter's syndrome in 1989-1990. Once you have an autoimmune disease you tend to collect others. MGUS origin is unknown, but since folks with celiac have a higher incidence of blood cancers there could be some link. A possible correlation between PTH and celiac is the malabsorption of nutrients, including minerals, from a damaged GI tract. Mostly one needs to limit the illnesses as well as you can with diet, meds (synthroid for me), exercise, and stress management.

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Yes I suffer from colitis too but never had a colon biopsy.
Usually in celiac people PTH tends to be high to balance the malabsorption, but in a very few cases celiac antibodies can destroy also parathyroid glands with hypoparathyroidism as a consequence. Its a rare consequence I have read on literature. But in my case I cant find these antibodies (in order to prove this). I can fix only 3 things: mgus, DQ8 and improvement of my health on gluten free diet. However hypoparathyroidism will last until I die. I must take calcium all life long

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My celiac was diagnosed soon after symptoms, so no long-term exposure to high levels of antibodies or visible damage on ileoscopy. I have the HLA-DQ8 0302 gene. My IgA, IgG, and IgM antibodies are all in normal range; bloodwork doesn't check for other antibodies. I have low C and D so take vitamins. I have a few symptoms of but no diagnosis of hypoparathyroidism, mainly bone spurs, muscle cramps, also an iregular heartbeat if I get glutened. You mentioned chemo and steroids, which aren't generally given for MGUS or celiac; steroids are sometimes given for colitis (mine is controlled by no NSAIDs [aspirin causes flares]). I did an elimination diet to see if I was sensitive to other foods. If you have a colonoscopy, ask them to also check for microscopic colitis (happens with celiac and the colon looks normal). The hardest thing about illnesses is the social isolation. This hit me soon after celiac diagnosis with comments (not being invited to dinners, fad diet…), and difficulties finding places to safely travel and eat. There are celiac disease support clubs that help with the isolation. I volunteer to counter the isolation. It is important to take care of yourself physically and emotionally. Autoimmune diseases don't seem to increase our risk of getting infected with nasty things like covid (we're more careful?) but could impact the severity. I got covid and glutened on a March bike tour, so a double cytokine storm ( vaxxed and boosted, but still felt like hell). I'm 69 and my diseases haven't limited me but living with them requires good swear words.

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Calcium is the basic therapy for the hypoparathyroidism. If calcium drops seroiusly I must get calcium intravenous bc it can lead to tetanic spasms of all the muscles.
Until now with oral calcium I can maintain a good calcium level in the blood.
I am 43. But after the first symptoms the gluten exposure went on for about six years when someone suggested me to run genetic test and endoscopic exam.
Covid made my liver suffer too, with hyper transaminasemia and abdominal pain for about 4 months, now all the labs are normal except for MGUS, calcium and PTH around zero.
Thanks for your support

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