Cardizem and Depression

I don't see depression or mood disorders listed in the several sources I checked. One professor at Harvard, Zusmann, feels that beta blockers can cause some mood alteration. Otherwise, no experience, either first or second-hand....sorry.
My guess, as uneducated as it is, is that you are experiencing the return of an 'old friend', brought chiefly due to recent changes in your circumstances and in your adaptation to them. I'm guess that, for example, you have also lost some sleep, and are not sleeping so great any more. That, alone, can cause mood changes, not to mention weight gain and suppression of one's immune response. You find yourself, alas, with more unwelcome items on your plate, and it makes you sad, anxious, maybe a bit at a loss.

Just being diagnosed with A-fib out of the blue with no clear "risk factors" except age was enough to depress me! I was so anxious for 4 weeks out of rhythm while I waited for cardioversion that I lost 6 pounds with out even trying! Iam on Cadizem too, but I haven't noticed any particular side effects BUT everyone is unique and with a history of depression in the past, it might make a difference. What helped me most is being able to talk to others like you who are dealing with the same feelings. I was too embarrassed to even tell people in the beginning! Hang in, try to relax, treat yourself well and ask your doctor! Hopefully you have a sympathetic one! Good luck!