Capecitabine side effects are really tough: What helps?

Posted by denise134 @denise134, Dec 20, 2024

Taking this drug finished 3rd cycle
1st 14 days was 3,900 mg day had severe mucositis with bleeding gums &scabs and bleeding nose sick stomach caused poor appetite but no nausea or vomiting - then 13th day diarrhea and blisters scabbing on chest so I quit 18 days not healed doc reduced dose 3,000 day

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Profile picture for gc4217 @gc4217

@115 did you also do mitomycin infusion day one. My treatments will be day 1 and day 29 mitomycin infusion plus capecitabine pills 2600mg 5 days a week with radiation. I start next week.

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@gc4217 @115 Eating and staying hydrated is important. There were times that I ate my way through nausea. It might not makes sense, but I found nausea is worse on an empty stomach.

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Profile picture for Turkey, Volunteer Mentor @tomrennie

@gc4217 @115 Eating and staying hydrated is important. There were times that I ate my way through nausea. It might not makes sense, but I found nausea is worse on an empty stomach.

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@tomrennie yes, I started right after diagnosis setting a schedule drinking water during the day to reach 96oz a day. I now can drink between 96 and 100 oz throughout the day with no problem. It even helped making my bladder hold more before using the restroom. I’m now working on small meals and making sure my skin is moisturized.

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Profile picture for gc4217 @gc4217

@115 did you also do mitomycin infusion day one. My treatments will be day 1 and day 29 mitomycin infusion plus capecitabine pills 2600mg 5 days a week with radiation. I start next week.

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@gc4217 no I’m not on mitomycin infusion.
Just the capecitabine and radiation 5 days a week for 6 weeks. They did mention IV chemo for 4 months after I finish with this treatment but hopefully this is all I’ll need.

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Profile picture for Turkey, Volunteer Mentor @tomrennie

@gc4217 @115 Eating and staying hydrated is important. There were times that I ate my way through nausea. It might not makes sense, but I found nausea is worse on an empty stomach.

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@tomrennie that’s how I am too usually when I’m nauseated.

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Have you consulted a Hemotologist, who is also an Onchologist?

My Oncologist from U of Chicago is also a Hematologist
who treats all kinds of cancers plus blood disorders.

For bleeding gums and mouth, etc I use "BIOTENE"
mouth wash that helped me a lot.

For diarrhea, mere adjusting dosage will not help. Like someone said, the med stays in the system for quite a while.
Take Imodium for Diarrhea and change your diet. Consult a dietician, who works w other care team members for you.
If you don't mind me asking, what kind of cancer or what is your current diagnosis?
Please reply.
Thank you for sharing info. You will get better every day.
Hang in there. Dear.
VJ

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Profile picture for denise134 @denise134

@tomrennie after 1 round of capecitibine 3900mg day
side affects were horrible and I was ready to quit but my pcp convinced me to stick with a reduced to 3000 mg day and I tried 2 more cycles and had to stop taking it but since I caught it early and no spread I am still cancer free since September 2024, still on surveillance every 3 months but now dealing with needing hip replacement.
Thank God for blessing me and ending cancer days.

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@denise134

If you go to hooded and do a search under the letter "c" for this medication, it gives info about possible side effects and how you can deal w some of them.
Good luck.
VJ

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If you go to goodrx. (Not hooded)
Please note this.
VJ

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Profile picture for GetWellSoon26 @vijay26

If you go to goodrx. (Not hooded)
Please note this.
VJ

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Profile picture for 115 @115

@gc4217 no I’m not on mitomycin infusion.
Just the capecitabine and radiation 5 days a week for 6 weeks. They did mention IV chemo for 4 months after I finish with this treatment but hopefully this is all I’ll need.

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@115 how are you feeling? Week 1 down. Keep us updated how your treatments are going. Wishing you the best through treatments. Are you using any nausea medication. They prescribed me Zofran.

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