Can anyone share their experience with Pluvicto?

Posted by vcash @vcash, Apr 22, 2024

My 85 year old dad has prostate cancer that has metastasized to his bones. Zytiga is no longer effective. He is considering Pluvicto. I would appreciate input from those who have used Pluvicto.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

jeff Marchi | @jeffmarc | Sep 25 5:56pm

In reply to @shz "@jeffmarc What if you have PTen and TP53 as well as ATM and BRCA?" + (show)

@shz
Got to admit, that’s a lot of genetic issues.

Are all 4 really found in one person?

I would not even try to make a guess.

jimw77 | @jimw77 | Oct 29 9:41am

In reply to @michaelbryan6998 "79 years young with metastacized Prostate Cancer in my ribs & backbone. I also have IPF...." + (show)

@michaelbryan6998
Michael, I hope that you've now had that fourth round of Pluvicto and the PSMA PET scan is now scheduled. I'm 77 years young, extensive mets, heart and other comorbidities, but taking it all as it comes and making the most of each day. Keep on keeping on.

michaelbryan6998 | @michaelbryan6998 | Oct 29 10:23am

In reply to @jimw77 "@michaelbryan6998 Michael, I hope that you've now had that fourth round of Pluvicto and the PSMA..." + (show)

@jimw77

thank you for your good thoughts. Pluvicto is on hold due to other medical issues, and yes, one day at a time and it all belongs to Him.

captainowow | @captainowow | 2 days ago

I'm 74 and have had stage 4 gleason 9 for 7+ years, and am on hormone therapy with a total of 45+ days of radiation. So far God's blessed me with a great oncologist and a great radiologist. Each time the identified areas of metastasized get addressed.
now I started my PLUVICTO treatment and only 14 days out and I still feel like crap. Max fatigue. Almost like my muscles and bones don't want to operate anymore. I can go for a daily 2 mile walk and I'm wiped out through 1/2 of the day. The last 4 days seems to have impacted my bowel movement as I have had to use the bathroom about every 30-40 minutes. Stools have been very very muddy (sorry to share). I'm getting about an average of 5 hrs sleep a nite and sruggle to fall asleep (if a all) again.
Nausea that just won't go away. I actually believe the anti nausea meds makes me feel worse. My next treatment is around Dec 21 (Merry Christmas!) and maybe i'll get a surprise gift.

jeff Marchi | @jeffmarc | 2 days ago

Some people react too strongly to Pluvicto and can’t continue with it.

Other people need to have a lower dose or have more time between Infusions.

You need to talk to your radiation oncologist about this problem. It is a very strong reaction and unusual. Get the doctor’s opinion on what to do next.