Long-term Antibiotics for Bronchiectasis & MAC

Posted by pejohnston @pejohnston, Feb 26, 2018

Diagnosed w/Bronchiectasis in 2008, MAC in 2011 and have been on many medications since then. Under control for several years, but reinfected a couple of years ago while on antibiotics. My body became somewhat immune to some of meds I was on. I am now taking several more drugs that have pretty significant side affects. Fortunately, I’ve been okay with them. Anyone else been on antibiotics for this length of time?

I have no feelings either way about my pulmonary doctor. My PCP is attempting to contact him and I trust her implicitly. She has questions about the use of the Big 3. Thank you for a sharing your journey. If I may ask, what other meds did you use to treat your MAC?

REPLY
@testlady

I have no feelings either way about my pulmonary doctor. My PCP is attempting to contact him and I trust her implicitly. She has questions about the use of the Big 3. Thank you for a sharing your journey. If I may ask, what other meds did you use to treat your MAC?

Jump to this post

Testlady, click on my photo icon to the left. My treatment plan is listed there. My plan may not work for others because it depends on the suseptibility test results to see if those meds would work. Sometimes the mac is resistant to some.

REPLY
@colleenyoung

Hi @pejohnston, Welcome to Connect. I modified the title of the discussion you started to distinguish it from the other discussions about antibiotics. I called it "Long-term Antibiotics for Bronchiectasis & MAC" to align with the question you asked to find out if other members have been taking antibiotics for an extended period of time, namely years.

You may also be interested in reviewing these discussions:
– (MAC/MAI) MYCOBACTERIUM AVIUM COMPLEX PULMONARY DISEASE/BRONCHIECTASIS https://connect.mayoclinic.org/discussion/mycobacterium-avium-complex-pulmonary-disease-macmai/
– MAC antibiotics and side effects https://connect.mayoclinic.org/discussion/mac-antibiotics-and-side-effects/
– Treatment Option https://connect.mayoclinic.org/discussion/treatment-option/

I'm also tagging @irene5 @sophie1019 @dmarks and @jenblalock on this discussion to share their experiences.
PEJohnston, do you tolerate the antibiotics well?

Jump to this post

can you tell me which 3 antibiotics you alternate with? Augmentin is one, but I do not know the others. Thank you, I would love to be able to take this to my Dr's appointment tomorrow.

REPLY

I don’t have MAC; instead I have an Achromobacter infection with my Bronchiectasis and am on a rotation of these 3 antibiotics: Augmentin, Doxycycline, and Bactrim.

REPLY
@janrn1

can you tell me which 3 antibiotics you alternate with? Augmentin is one, but I do not know the others. Thank you, I would love to be able to take this to my Dr's appointment tomorrow.

Jump to this post

Hi Jan. please click on my photo icon at the left to see the three drugs used and duration. In a nutshell: doxycycline, ciprofloxacin, and inhaled tobramycin. Nebulizing 7% saline (sodium chloride) really helps to keep the mac down or gone. Be sure to ask your dr about that. Good luck with your dr visit.

REPLY
@windwalker

@pejohnston , Hello, and welcome to the Connect community. Do you have a a first name that you would like to use? To answer your question about long term antibiotics; you will see that many of our members are on a long term regimine. Most that are taking antibiotics are taking the 'Big 3' cocktail. People usually are on them anywhere from 18 months to 3 years. I am on a different kind of ongoing regimine. I have been taking alternating singular antibiotics on alternating months. I have been doing this since 2013. It is known as a prophylactic approach. My doctor explained that he liked this approach because it is more tolerable for the organs and prevents the mac from becoming resistant to the antibiotics.

Jump to this post

Can you tell me which 3 antibiotics you take for MAC?

REPLY
@ckscoville

I don’t have MAC; instead I have an Achromobacter infection with my Bronchiectasis and am on a rotation of these 3 antibiotics: Augmentin, Doxycycline, and Bactrim.

Jump to this post

Hi ckscoville, I was curious about your particular organism, so I looked it up. I thought this tidbit about antibiotics might be useful for you. It is usually resistant to a variety of antibiotics including penicillins, ; cephalosporins, quinolones, and aminoglycosides. Ampicillin and carbenicillin, which are penicillins, are an exception. It is variably susceptible to tetracyclines, chloramphenicol, trimethoprim-sulfamethoxazole, and colistin.[7]

REPLY
@windwalker

Hi ckscoville, I was curious about your particular organism, so I looked it up. I thought this tidbit about antibiotics might be useful for you. It is usually resistant to a variety of antibiotics including penicillins, ; cephalosporins, quinolones, and aminoglycosides. Ampicillin and carbenicillin, which are penicillins, are an exception. It is variably susceptible to tetracyclines, chloramphenicol, trimethoprim-sulfamethoxazole, and colistin.[7]

Jump to this post

Thanks. I have the feeling that my doctors at Mayo are still trying to figure out the best approach. The rotation of different antibiotics is what they just started in July, but I've been dealing with this bacteria for at least a year and a half.

REPLY
Please sign in or register to post a reply.
  Request Appointment