Bladder Cancer: High grade

Did you have side effects from the Adstiladrin?

I just saw your update…

In 2023 I was diagnosed with high grade non invasive papillary bladder cancer. Had 3 BCG treatments but started to have complications with this so went on the Gem/doc treatments for a year. Had 1 tumor to recur. Now on maintenance & will have another cystoscope in 2 months. Adstiladrin is a new drug that sounds very promising…has your doctor recommended this?

My low grade NMIBC was found December 2023. I had the a TURBT in January 2024, one intravesical treatment of Mitomycin and then six BCG treatments through the spring, I was in remission by June 2024, then the doctor discovered high-grade NMIBC with CIS in January 2025, for which I did not have surgery, but received Adstiladrin in March and then again this month. There is no evidence of cancer as of June 4, 2025.

How did it go, just been diagnosed with T2 highly invasive muscle cancer and have been recommended bladder removal, which I’d like to avoid

Discuss trials and the adstiladrin just mentioned. Also ask on BCAN (Inspire), Reddit and Facebook.

I hope for some feedback as well

I am hoping someone who has never been NED AFTER EVERY ROUND OF BCG..6 rounds oh dem doc intravesically..going on 5 th Turbt since oct 2023..high grade. Papillary. Surface only in bladder..no laminated invasion….so I want to try this before I remove my bladder..hopefully someone has a successful story to tell…..

Anyone have success with Adstiladrin?

RC depends on pathology. Most often it is not required. In other cases it is the best choice without delay. CTDNA is really key in assessing risk as is imaging.

My turn around was 10 to 11 weeks. Symptoms late August. Cystoscopy mid-September. TURBT 1 mid-October. TURBT early November. RC mid-November. I skipped NAC as it is not indicated for PT1A. Turned out it was PT3AN1M0 because of diverticulum which is a high risk factor due to absence of muscle wall.