Best time for exemestane?

Posted by mistymar @mistymar, May 26 9:05pm

I’ve been on exemestane for about 16 months. Taking it at dinner time because it needs to be taken with food and that is my most consistent meal. Extreme fatigue started at 4 months - HAD to take a nap mid afternoon or would actually fall asleep in the middle of things. All tests were normal. Then at 7 months the insomnia started which of course made the fatigue worse - lucky to get 3 hours of sleep. This made exercise more difficult (couldn’t do a full mile anymore without stopping 5 or 6 times). Other side effects of course but these were the major ones. He took me off at the last visit for 4 weeks which I extended to 6 because it took that long for me to actually feel like it’s worth living. Started melatonin and currently getting about 6-7 hours of sleep and doing much better otherwise. He wants me back on the exemestane to see if all my symptoms were just because of a lack of sleep and not because of the medication. Trying to find out recommendations for when to take it. Maybe better in the morning? Should I try for mid-day to try to change when it actually peaks? Any suggestions will be much appreciated.

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@mistymar, you may also be interested in the tips shared in this related discussion:
- Timing of aromatase inhibitors (AIs) - taking day or night?https://connect.mayoclinic.org/discussion/timing-of-hrt-anastrozole-taking-day-or-night/

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