1. < Post-COVID Recovery & COVID-19

Anyone Tried Monoclonal Antibody Treatment?

Posted by repl @repl, 4 days ago

I’m wondering if anyone out there has tried monoclonal antibody treatment? If so, what were their symptoms prior to treatment and after?

Also, does anyone know the outcome of the UCSF study for this? Are results out yet?

I read a case study of 3 LC who had complete recovery within days! https://www.sciencedirect.com/science/article/pii/S073567572300534X

I’d like to know if this is possible for those who have older versions of the virus?

Interested in more discussions like this? Go to the Post-COVID Recovery & COVID-19 Support Group.

Mentor
John, Volunteer Mentor | @johnbishop | 4 days ago

@repl, I had the monoclonal antibody treatment the first time I contracted COVID-19 and it did provide relief within a few days for me. The second time I contracted COVID I wasn't eligible for the treatment because it had been too long (more than 10 days) after noticing my first symptoms. The second time I had a really mild case and it didn't really even feel bad. I haven't read the UCSF study but Mayo Clinic has a Q and A on the topic here:

"Monoclonal antibody therapies are laboratory-produced proteins that serve as temporary immunity against COVID-19. The antibodies bind to SARS-CoV2, the virus that causes COVID-19, and prevent it from attaching to human cells."
-- Mayo Clinic Q and A: COVID-19 treatment options
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-covid-19-treatment-options/

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1 reply
dloos | @dloos | 4 days ago

It has been my understanding that this is used for active Covid only, similar to how Paxlovid is used.
As far as I know they have not found either effective for long Covid.

So far long Covid treatments are targeting symptoms with limited success.
My personal experience has been conventional treatment for my symptoms is worthless.

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repl | @repl | 4 days ago
In reply to @johnbishop "@repl, I had the monoclonal antibody treatment the first time I contracted COVID-19 and it did..." + (show)
@johnbishop

@repl, I had the monoclonal antibody treatment the first time I contracted COVID-19 and it did provide relief within a few days for me. The second time I contracted COVID I wasn't eligible for the treatment because it had been too long (more than 10 days) after noticing my first symptoms. The second time I had a really mild case and it didn't really even feel bad. I haven't read the UCSF study but Mayo Clinic has a Q and A on the topic here:

"Monoclonal antibody therapies are laboratory-produced proteins that serve as temporary immunity against COVID-19. The antibodies bind to SARS-CoV2, the virus that causes COVID-19, and prevent it from attaching to human cells."
-- Mayo Clinic Q and A: COVID-19 treatment options
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-covid-19-treatment-options/

Jump to this post

Hi John,
Thank you for your response.

It sounds like you got the monoclonal antibodies for acute infection, which helped. And possibly helped with your future infections as well…

I’d be super interested to know of anyone who has had monoclonal antibodies after having long COVID? Not acute infection.

The study I linked to discussed how these patients had LC and were given monoclonal antibody therapy with remission after few days of treatment. I think this is really promising!

So just wondering if anyone out there has heard of someone taking monoclonal therapy for LC?

And it’s good to hear from someone who has had it done too!

Did you have any side effects from it?

Best,
REPL

REPLY
1 reply
Mentor
John, Volunteer Mentor | @johnbishop | 4 days ago
In reply to @repl "Hi John, Thank you for your response. It sounds like you got the monoclonal antibodies for..." + (show)
@repl

Hi John,
Thank you for your response.

It sounds like you got the monoclonal antibodies for acute infection, which helped. And possibly helped with your future infections as well…

I’d be super interested to know of anyone who has had monoclonal antibodies after having long COVID? Not acute infection.

The study I linked to discussed how these patients had LC and were given monoclonal antibody therapy with remission after few days of treatment. I think this is really promising!

So just wondering if anyone out there has heard of someone taking monoclonal therapy for LC?

And it’s good to hear from someone who has had it done too!

Did you have any side effects from it?

Best,
REPL

Jump to this post

I didn’t have any side effects to that I can remember. I did have the Paxlovid treatment for the second time I had COVID and it worked also but it took a week before I felt better.

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1 reply
klehker | @klehker | 4 days ago

I had a monoclonal antibody infusion (Pemgarda) last week. I got it because I am immune compromised (kidney transplant recipient) and therefore qualified for this emergency authorization medication to prevent Covid. I have not previously seen the case study you cited, or heard about MCA as treatment for long Covid.
My LC journey started about a year ago. Main symptoms are sleep disruption, body aches, abdominal pain, fatigue, headaches, chills, nausea.... Like most people, my diagnosis came after my docs ruled out many other things. By December I was much improved, but then I got Covid again, and all of my LC symptoms returned.
Wouldn't it be great if my Pemgarda infusion cured my LC! I will keep you posted.

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1 reply
repl | @repl | 3 days ago
In reply to @johnbishop "I didn’t have any side effects to that I can remember. I did have the Paxlovid..." + (show)
@johnbishop

I didn’t have any side effects to that I can remember. I did have the Paxlovid treatment for the second time I had COVID and it worked also but it took a week before I felt better.

Jump to this post

Very interesting that the MCA worked better than Paxlovid. And no side effects!

Thank you for sharing this!

REPLY
repl | @repl | 3 days ago
In reply to @klehker "I had a monoclonal antibody infusion (Pemgarda) last week. I got it because I am immune..." + (show)
@klehker

I had a monoclonal antibody infusion (Pemgarda) last week. I got it because I am immune compromised (kidney transplant recipient) and therefore qualified for this emergency authorization medication to prevent Covid. I have not previously seen the case study you cited, or heard about MCA as treatment for long Covid.
My LC journey started about a year ago. Main symptoms are sleep disruption, body aches, abdominal pain, fatigue, headaches, chills, nausea.... Like most people, my diagnosis came after my docs ruled out many other things. By December I was much improved, but then I got Covid again, and all of my LC symptoms returned.
Wouldn't it be great if my Pemgarda infusion cured my LC! I will keep you posted.

Jump to this post

Hi klehker!
Thanks for sharing your experience!

I’m SUPER interested to know how MCA goes for you! When did you last get Covid?
How many MCA sessions will you be getting?

You mentioned getting MCA treatment last week, have you noticed any changes?

I’d love to know how your journey goes! Please keep me posted 😁

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