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Anyone have severe bone (spine) loss with recurrence of PC?
Had RALP 1/2022, ADT, Lupron for 2 years and PSA 0 through last test 09/25.
Now I have compression fractures in vertebrae T5, T7, & T9.
Symptoms of bad pain came on fast.
Will have Kryphoplasty very soon.
Could this be PC coming back super fast?
Thanks for any insights.
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As soon as you went on Lupron you were supposed to get a DEXA scan to see what your bone strength is and Instructions to take calcium at least twice a day, (calcium citrate preferably).
Soon after I went on Lupron, I was put on Fosamax. It’s a bone strengthening pill you take once a week. After six years of that I went on Zometa infusions, but you can also get Xgeva infusions. Either one keeps your bones, strong and prevents them from fracturing.
You should speak to your doctor about this. It’s probably time for you to do at least one of the bone strengthening drugs.
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2 ReactionsHad Prolia from start of Lupron. Taking calcium since ending Lupron. DEXA done twice. Before RALP and about 6-months after ADT stopped. I was 70% to the good side for my age, 78.
I’m worried that since sore back didn’t start till just after last PSA, 9/25, that PC has come back super fast deteriorating 3 vertebra.
But never heard PC causing bone loss. Thought it only made tumors.
Worried and confused.
Will request biopsy of bone for PC or other culprit during repair
@grandpun
One of the primary problems that Lupron causes is thinning of The bones. There was a doctor at one of the conferences about nine months ago, that specialize in bone health and said that everybody who is castrate resistant Should be on bone strengtheners. He emphasized that Lupron is really hard on the bones, And those were on it long-term should be on Strengtheners.
I forgot to mention that vitamin D is another one of the important things needed for keeping bones strong. That was another thing. My doctor mentioned I needed to take daily. I’m sure you’re doing that..
From AI
Lupron can cause bone loss (thinning of the bones) as a side effect, particularly with long-term use. This is because it can decrease sex hormones, which are important for bone density. Doctors can mitigate this risk by using "add-back" therapy with a progestin like norethindrone acetate, ensuring adequate calcium and vitamin D intake, and monitoring bone mineral density with DEXA scans.